Factors @ Stark Lab

Gene Name Type Activity (log2) in S2 cells
(avg/min/max)
Cluster Data available
S2Kc167BG3OSCHeLa
Sin3A (FBgn0022764) cofactor
 
(-1.65/-4.19/-0.97)

Factor activity

Additional information

Sin3A [FlyBase] | Sin3A [FlyMine] | Sin3A [BDGP]

H. sapiens orthologues1

SIN3B (HGNC:19354, ENSG00000127511), SIN3A (HGNC:19353, ENSG00000169375)

Functionally similar transcription factors and cofactors

CDS DNA Sequence2

ATGATGAAACGCACTCGCGTAGACGAGGTGCAATTTGGCACACGACCCGTTCCTCAGACCTCCGGAGGTGTGGGCGTTGGTGTCGTCGGCGTAACTGGAGGTGGGCCAACATCCGGCGGCGGTGGCACTGCTACTGTGGGCGTCAATACGACGGGCGTTACCATTGGTACCGTCGTGCCCAGTGCTCATAACGCCACCATCAGCGGGATCGGTTCCATTCACCATCGCATCCTTACTCCACAGCATGGAGGAGCACAAACCATTGCCTATTTGCCGTCCACCACGCCGACGGCTACGAATTTGAAGACCACAACCTCGATTGTGGATAGCACTACCGCTGGAGGACCAGTAGGAGCAGGAGCACAGGTGGCCGTAGGAGTTGGCTCTGCAGCCGGCGGAGGAGGCGTGGTGGTCTCCACAGGGAGCACGGGAACGCAAACATTACAGTATACAACATCTTATAGTGTGGCTTCGATACAGGCTGGTGGAACTCTGAAAGCCAACACAGCGGATGGCGCGAACACGGTACAGATTCATGTCACAGGAGGAGGAGCTGCAAACAATCCTGCCAGTGCACAGACTGTTTCCAGCAGCTCACAAACGGGCACAATCCGTCAGCGTACAATCAGCGGCACCCAGACAGTGGCCACTGCAGTGGGTAATCTAGCCACGATTTCCCAGCAACAACCGGTTCAACAATCACCTTTGGGCAAGGCCCAAACGCCTCCATCGTCCGTGGTTGCCAACAGTATCCCAGTGGGTGGAACCACCCCACCACAAGGACAGTCGGGAAATGCCACGCCACGCTTAAAAGTGGAGGATGCGTTGAGCTACCTGGACCAAGTAAAGTACCAGTATGCAGACCAGCCGCAAATCTACAACAACTTCCTCGACATAATGAAGGAATTCAAGTCGCACTGCATCGACACACCCGGAGTGATTGAGCGAGTCTCCACACTCTTCAAGGGGCACACAGAGCTGATATACGGCTTCAACATGTTCTTACCGCCGGGTTACAAGATCGAAATTCATTCGGATGCTCTTGGCTGTTCGGTGCCGGTGGTTTCGATGCCCTCACCACCGGGAGCGCCAACGAGCACAGGAACGGTGCATATGCTCACCGGAAATAGTTCGATGTCCGGTGCCGGACATATCGCCATCAAGACGACCAATGCTGCGACTTTAACACCGGCAGCAGGGGCTGGAGCAGCGGCCGCAGCAGCAGCTGTGGCTCAGATTCAATCCGCTGGAGCTGTAAATCTAATGACCCACGGCGGAGCCTCGCTTACCCAGACCACTATTCATGCATTGCAACAGGCGACGCCTCCTCAATCACAATCTCCAGGCGGAGGTCATGTCCACGTGAGTGTAACAAACTCTACGGCAGCAAACGCCGTAGTGCCCGGACAGCCAGGCATCTCCGTATCGGCGCACAATGTACCGCAGAACTACTCGAGAGATCGAGAAAGGGCCACCATAACACCTACTGGGCAAGTGGCTGGAGCAGCGGCAAACGTGAATGCGTCTGCTAGTATAGTTGTCGGTGGACCTCCAACGCCCAATTCTCTAAGTGAGCTTAGCCCTCATGGAGGAGCAGGAGGTGGGCCAGGTGCGGGAGCGGCGCAGCACAATCTGCATCACATCCAGCAGGCGCATCAATCGATTTTGCTTGGGGAGACGGGACAGCAGAATCAGCCGGTGGAGTTCAATCACGCCATAACCTATGTAAATAAGATCAAGAATCGTTTCCAAAACCAGCCGGCCAAGTACAAGAAATTCCTCGAAATTCTGCACGATTATCAGAGGGAGCAAAAGGTGATGAAGGAGGGCAGCCTGAACCAGGGTAAAATGCTCACCGAGCAGGAGGTATACACGCAGGTGGCTAAGCTTTTTGGCCAGGATGAGGATTTGCTTAGAGAGTTTGGCCAGTTTCTTCCTGATGCCACCAACCACCAGTCCGGGCAGTACATGTCCAAGTCAGCGTCTGTGCACAATGACCATGGCAAGCGTCCCACGGCTACTTTAAGCGGTGGAGCTCACATAACCATGTCATCTGCTTCGCCAGCGCCAAGTGGATCCCCTCTGCATTTGGGTGCAACGACTCTTCCGCAGATCGACAAAAGCGCCCATGCAGCGGCCATAGGAAACCTTTCGGCGGTGAACACTAGTGTCAGCATTAAGACGTACAATAATAATCAGCAACAGCAGAATCATGTGATCGGTTCAGGGCTGAATGCGACGCGGAACGATATTCTCTTTGAGAAGGACTATCACGCGGGTCTGCAGCAGCAAGCGCATCAGCGAGGAGCTGGAGTTGGAGGCCATCATCATTTGGCCGGGACTGCAGCGGGCGCCAATATCGGACGGCCTGGAGTGGGAGCCAGCGTGATGGTGTCGTACGATAAAGAGCATCGAAATAATCATCATGTACAAAAGTACGTTGGCCACGCGCCAAACCAGAATCTAACGCATGGTCATAACGCAAAGAAATCACCAAGTTATGGCATTCCTTCGGTGATTGGTTCCATGCCGCACATTTCGGACAATTCGCTCGACCGCAGTTCACCGGGAATTAGTTACGCCACGCCACCATTGCCCTCTGGTCCACATGGACAGCATAACTCTGGTTCAGCTACGAGGAGGCCGGGTGATGACAGTTTAGTCGGACACTATGCTAGTGGAGCGCCGCCTGCTAAGCGACCGAAGCCTTATTGTCGTGATGTCAGCTTTTCCGAAGCATCGAGCAAGTGCACCATCTCCGACGCCGCGTTCTTTGACAAGGTGCGAAAGGCGTTGAGAAGTCCAGAGGTCTACGACAACTTCCTGCGATGCCTGACCCTTTTTAACCAGGAAATTGTCTCCAAAACGGAACTTCTTGGTCTGGTATCACCGTTCTTGATGAAGTTCCCCGACCTGCTGAGATGGTTCACCGACTTTCTGGGACCGCCCTCTGGTCAACCTGCTGGAGGATTGATTGACGGCATGCCCTTAGCCGCAACGCAACGTCAGGGAGGTGGAAGCAGTAATAGTTCCCATGATCGAGGTACCAGTCACCAGAGTGCCGCCGAGTATGTCCAGGATGTGGATCTGTCTTCTTGCAAGCGGCTGGGTGCATCCTATTGTGCTTTGCCGCAGTCCACAGTACCTAAGAAGTGCAGCGGACGGACGGCTCTCTGCCGGGAAGTGCTCAACGACAAATGGGTATCGTTCCCGACGTGGGCCAGCGAGGACTCCACTTTTGTTACATCGCGAAAAACTCAGTTCGAGGAGACAATTTACAGAACGGAGGACGAGCGATTCGAGCTGGACCTGGTCATCGAGGTTAATAGTGCCACGATTCGAGTGCTGGAGAACTTACAGAAGAAAATGTCACGAATGTCCACCGAGGAATTGAGCAAATTCCATCTGGACGATCATCTGGGCGGCACATCTCAAACGATACACCAGCGGGCCATTCATCGCATCTACGGCGACAAGTCGGGAGAGATAATCACGGGAATGAAGAAAAATCCGTTTGTGGCGGTGCCTATTGTACTGAAGCGACTGAAAGTCAAGGAGGAGGAGTGGCGAGAAGCGCAAAAGACCTTCAATAAGCAATGGCGGGAACAGAACGAGAAGTACTACCTCAAGTCTCTCGATCACCAGGCCATCAACTTTAAGCCCAACGACATGAAAGCCCTGCGCTCAAAGAGTCTGTTTAACGAAATCGAGACGCTGTACGATGAGCGGCACGACCAAGAGGACGACGCCATGGAACCGTTTGGGCCGCATCTGGTGCTGCCGTACAAGGATAAAACCATTCTGGACGATGCCGCCAACCTGCTGATTCATCATGTGAAGCGTCAGACTGGCATCCAGAAGCAGGAGAAGCAAAAGATTAAGCAGATCATCCGACAATTTGTGCCTGACCTTTTCTTCGCGCCGCGACAGCCACTAAGCGATGACGAACGCGATGACGATGACAATACGAAAATGGACGTGGACTCGCCACTGGGTCGCACGGAGTCTTCGACTCGAAATGCCAAGAGTACGCCCAGTGAAAGTGCCTCTCCGGCGCGTAGCAATGCAAGCACTAGCAGCGTAACACCAGCGGGAATTAAGAAAGAGACTGATGACTCGAAAGCGACGACAGGATCTTTTGCACCAGCGTCCTCGGCAACGGCATCTTCAGCGACGCCTGTGGACGATGCTACGCCATCAACATCCTCAGCAGCGGCGGCAGCATCAGCGGCATCGTCATCAACTGTTTCAGGAACCGAAGGCAAGCCAAAGGATGACCCCCTATCGTCGCACAAGGAAGAAGGAGCCGGTAGCACCAGCTCTGGAGTTGCCACGAGTCCCAGGCAAGCCCAAGACACTGCAGGAGCAGGCGTCGATGTGGAAATCAAACTGGAACATCCTGCGGACTTTTCCAATCCAAAGCTTCTACCGCCGCACGCGCACGGGCAACGCGAAGACGAATCCTACACGCTGTTCTTCGCTAACAACAATTGGTATTTATTCCTGCGGCTACATGCGATTCTCTGCGACCGTCTGCATGTTATGTATGAAAGAGCGCGTTTGCTGGCCATCGAGGAGGAGCGCTGTAGGGTGAATCGAAGGGAGAGCACAGCCACGGCGCTGCGGCTAAAGCCCAAACCGGAGATTCAAGTTGAAGACTACTACCCCACCTTCCTTGATATGCTCAAGAACGTCCTAGACGGCAACATGGACTCGAATACGTTCGAGGACACGATGCGTGAAATGTTTGGCATTTATGCCTACATCTCTTTCACGCTGGATAAGGTTGTCTCCAATGCTGTTCGCCAGCTGCAATATTGTGTCACAGAACGAGCCGCACTGGATTGTGTAGAGCTGTTTGCAACGGAGCAAAGGCGTGGCTGCACCGGAGGATTCTGTCGAGATGCGCACAAGACATTTGACAGGGAGATGTCGTATCAGCGGAAAGCTGAGAGCATTCTCAACGAGGAGAATTGCTTCAAAGTGTACATTTACAAAATCGATTGCCGTGTAACCATAGAGCTGCTTGATTCGGAGCCCGAGGAAGTCGATAAGCCGGCTGCGTTGAAGGCCCAGAAGTTCAGCAAGTATGTAGAGCGGTTGGCGAATCCTGCGCTCGGCGGTGGTGGCAATACTGGCCGCTCCGATTCGGCGCTCGGCAATGACAGCGTTGTAGATGGGTCCGATATCAAGACGGAGGCGGACGAAGATACTGCCGAGTTGCGCTACAGAGAAGGTGGAATCGGAGGAGCAGGCAAGGCGCGCTTTTTGGTGCGCAACAAGCGGAGATCAAAGCTGCTTGAGGAGCAAGTGCGTCAGTTGTTTGAACATAGGCGGAATCGGATTGAGCAGCATGGTACTGCGGCCTCACTTGAACCCATCTCCGTTGACAGTGCCATTTCAAGCAACAGCACCACCGGCGGTGGCGGCAGCGGCACTAATAACAACAATAATAATAATAATAATAACAACAGCTGGGGCGGCAAACGTCTGGAGAGGCTGGGCGCCCCACAGGTGGGCTTGGCCGAGCAATACGCCTTTAATGATCGCGACGAGATCAGCACAAATATCAGCAACGGGCGATGTTTTGTGACCAGCAAGAATCTCAAGCTACTTAAGTACGATGCAGTGCGTCGTGCCAAGAAGAGTCATTGCCGCGTAACTCAGGCGAAATACGCTCACTTCCAAACGTACGTTAACAAGTGGCTTCAGCAACATGTCAGCGAGCAACAGCAGCAGAACTGCGTCGACTGGCTGCTGGGCAAGACGGCAGACCAAATCAATGCCAGCGGCTGGGGATCCGCCAGCAAAACCAAGACGGTACAGCAGAAGGATACTTCGAAGACACCGTATCGCATCTACAACAGATACAGAGTGGTGCAGAGTGCAGTAAGCGGCGGTTTGATGAGTGCCACTGCTCCAACTCCAGATGGTTCAGTTCCGGCGGTCAATTCCGCGCCATCAGGCTCAGTTTCAACGGTGAACAATGTACAGGGCTCGGCGGCAGTATCCTCAACTTCCCACTCGATGTGCAACAGTAGCATTTTGTCCGCGGACTCCACCACCAATACCAATGCGTCAGCACAGCAGCAGCAGCATTGCAACAGTGCAGCAGCTGCAACAACACCGAATGCAGAGGCACTGCAACAGGTGCGACCCATGGAGAGC

CDS AA Sequence2

MMKRTRVDEVQFGTRPVPQTSGGVGVGVVGVTGGGPTSGGGGTATVGVNTTGVTIGTVVPSAHNATISGIGSIHHRILTPQHGGAQTIAYLPSTTPTATNLKTTTSIVDSTTAGGPVGAGAQVAVGVGSAAGGGGVVVSTGSTGTQTLQYTTSYSVASIQAGGTLKANTADGANTVQIHVTGGGAANNPASAQTVSSSSQTGTIRQRTISGTQTVATAVGNLATISQQQPVQQSPLGKAQTPPSSVVANSIPVGGTTPPQGQSGNATPRLKVEDALSYLDQVKYQYADQPQIYNNFLDIMKEFKSHCIDTPGVIERVSTLFKGHTELIYGFNMFLPPGYKIEIHSDALGCSVPVVSMPSPPGAPTSTGTVHMLTGNSSMSGAGHIAIKTTNAATLTPAAGAGAAAAAAAVAQIQSAGAVNLMTHGGASLTQTTIHALQQATPPQSQSPGGGHVHVSVTNSTAANAVVPGQPGISVSAHNVPQNYSRDRERATITPTGQVAGAAANVNASASIVVGGPPTPNSLSELSPHGGAGGGPGAGAAQHNLHHIQQAHQSILLGETGQQNQPVEFNHAITYVNKIKNRFQNQPAKYKKFLEILHDYQREQKVMKEGSLNQGKMLTEQEVYTQVAKLFGQDEDLLREFGQFLPDATNHQSGQYMSKSASVHNDHGKRPTATLSGGAHITMSSASPAPSGSPLHLGATTLPQIDKSAHAAAIGNLSAVNTSVSIKTYNNNQQQQNHVIGSGLNATRNDILFEKDYHAGLQQQAHQRGAGVGGHHHLAGTAAGANIGRPGVGASVMVSYDKEHRNNHHVQKYVGHAPNQNLTHGHNAKKSPSYGIPSVIGSMPHISDNSLDRSSPGISYATPPLPSGPHGQHNSGSATRRPGDDSLVGHYASGAPPAKRPKPYCRDVSFSEASSKCTISDAAFFDKVRKALRSPEVYDNFLRCLTLFNQEIVSKTELLGLVSPFLMKFPDLLRWFTDFLGPPSGQPAGGLIDGMPLAATQRQGGGSSNSSHDRGTSHQSAAEYVQDVDLSSCKRLGASYCALPQSTVPKKCSGRTALCREVLNDKWVSFPTWASEDSTFVTSRKTQFEETIYRTEDERFELDLVIEVNSATIRVLENLQKKMSRMSTEELSKFHLDDHLGGTSQTIHQRAIHRIYGDKSGEIITGMKKNPFVAVPIVLKRLKVKEEEWREAQKTFNKQWREQNEKYYLKSLDHQAINFKPNDMKALRSKSLFNEIETLYDERHDQEDDAMEPFGPHLVLPYKDKTILDDAANLLIHHVKRQTGIQKQEKQKIKQIIRQFVPDLFFAPRQPLSDDERDDDDNTKMDVDSPLGRTESSTRNAKSTPSESASPARSNASTSSVTPAGIKKETDDSKATTGSFAPASSATASSATPVDDATPSTSSAAAAASAASSSTVSGTEGKPKDDPLSSHKEEGAGSTSSGVATSPRQAQDTAGAGVDVEIKLEHPADFSNPKLLPPHAHGQREDESYTLFFANNNWYLFLRLHAILCDRLHVMYERARLLAIEEERCRVNRRESTATALRLKPKPEIQVEDYYPTFLDMLKNVLDGNMDSNTFEDTMREMFGIYAYISFTLDKVVSNAVRQLQYCVTERAALDCVELFATEQRRGCTGGFCRDAHKTFDREMSYQRKAESILNEENCFKVYIYKIDCRVTIELLDSEPEEVDKPAALKAQKFSKYVERLANPALGGGGNTGRSDSALGNDSVVDGSDIKTEADEDTAELRYREGGIGGAGKARFLVRNKRRSKLLEEQVRQLFEHRRNRIEQHGTAASLEPISVDSAISSNSTTGGGGSGTNNNNNNNNNNNSWGGKRLERLGAPQVGLAEQYAFNDRDEISTNISNGRCFVTSKNLKLLKYDAVRRAKKSHCRVTQAKYAHFQTYVNKWLQQHVSEQQQQNCVDWLLGKTADQINASGWGSASKTKTVQQKDTSKTPYRIYNRYRVVQSAVSGGLMSATAPTPDGSVPAVNSAPSGSVSTVNNVQGSAAVSSTSHSMCNSSILSADSTTNTNASAQQQQHCNSAAAATTPNAEALQQVRPMES

1   H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
2   Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.