Factors @ Stark Lab

Gene Name Type Activity (log2) in S2 cells
(avg/min/max)
Cluster Data available
S2Kc167BG3OSCHeLa
MTA1-like (FBgn0027951) cofactor
 
(-1.39/-4.13/-0.46)

Factor activity

H. sapiens orthologues1

MTA1 (HGNC:7410, ENSG00000182979), MTA3 (HGNC:23784, ENSG00000057935), MTA2 (HGNC:7411, ENSG00000149480)

Functionally similar transcription factors and cofactors

CDS DNA Sequence2

ATGGCCACAAATATGTATCGAGTCGGAGACTATGTTTACGTTGAGACAACGCCGAACAGTCCCTACTTAATACGACGCATCGAGGAGCTGAACAAAAACCAAACCGGCAATGTGGAAGCGAAGGTCATGTGCTTCTACCGCCGCCGGGATCTGCCCAATCCGCTCGTGCAATTGGCCGACAAACACCAACCTGCCCTGGATGAGGAGCGCACCAGTCCAACGCAAACGTCTGGCGGAGGAGGCTCAGCCACCGGGAACTCCGGCAGCAACAGCAGCGGCACTTCCAACAACAACAGCAGCAGCACTGCCATCGGAGGTGGAGCGGGAGGCTCCGGAGGTGCAGGAGGCGACGCGGAGAAGGGCGAAGCGTTGACCAGCAAGCAGCGCTATCAGATCAAGCACCGCGAGCTATTTCTGTCACGCCAAGTCGAGTCGATACCCGCCACACAGATCCGAGGCAAGTGCTCGGTGACCCTGCTCAACGAGACGGAGTCCCTGCAGAGCTATCTTAATAAAGACGACACATTCTTCTACTGTCTGGTGTTCGATCCAAATCAAAAGACGCTGCTTGCCGACAAGGGCGAGATCCGGGTCGGCAGTCGCTACCAGTGTGATATACCCGCCAAGCTCAAGGACACCGCCACCGACGACCGCAAGCTGGAGGAACTCGAATCGCTGGTGTGGACGCCGGAGCACAGCCTGACCGACCGCAAGATAGACCAGTTCTTGGTCGTGTCACGCTCCATCGGCACCTTCGCCCGCGCCCTGGACTGCAGCAGTTCGGTGAAGCAGCCCTCGTTGCACATGTCCGCCGCGGCGGCCAGCAGGGACATCACACTGTTTCACGCAATGAACATTCTGCACAAGCACGAGTACTCTATTGAAGAGTCCATGTCGTCGCTAGTTCCTTCCACTGGGCCTGTGCTATGTCGCGATGAAATCGAGGACTGGAGCGCATCGGAGGCGAATCTTTTTGAAGAGGCGCTAGAAAAATATGGCAAAGACTTTAATGACATTCGACAAGATTTCCTGCCTTGGAAAACGCTGAAACAAATCATCGAGTACTACTACATGTGGAAGACCACCGATCGCTACGTGCAGCAGAAGCGAGTGAAGGCCGTCGAGGCGGAGCTGAAGCTCAAGCAGGTCTACATACCACAGTATAACAACAATGGCAAGGGGAACGGAACGTCTACGAAGGCGGGAGGTGGCATCTATAATGGAACCACAAACGGGAGCACAGATCTCTCCAGCAATGGCAAGCCATGCGAATCGTGCGGTACAACGAAATCATCACAGTGGAACTCGGTCAGCAGTGGGCACAGTACGAGCCGCCTTTGCCTGAGCTGCTGGGAGTACTGGCGGAGGTACGGCAGTATGAAGTCGGCGACCAAGGGCGATGCTGGCGAAGGCGACGCCAAGAAGAAGTCATCATCGGCAGCGTCGACGCCGACAGCCACGTTAGCGGGTCTAGCTACAACGCCCACGGCTGTGGTCGACCTGAATGATGACGAGAAAATCAGTGATCTTACCAATCGTCAGTTGCACAGATGTTCTATTGTCAATTGCGGCAAGGAGTTCAAGCTTAAGACTCACCTGGCCCGCCACTATGCGCAAGCGCACGGCATCGCCATCAGCTCCGGATCGCCGCGGCCCATAATGAAGACGCGCACTGCCTTTTACTTGCACACCAATCCCATGACACGGGTGGCGCGTGCTATCTGCCGCAGCATCGTGAAGCCGAAGAAGGCGGCGCGACAGAGCGCGTACGCGATCAATGCCATGCTGGTGAAACAAGAATTTACAAATCGTATTAGTGGAAAATCGCAGGCGGAGATCAAGAAGTTGCTTTTGCTGAAGCCCAAGGATCGGGGTAGTGTCACCAAGATTGCCAACCGCCTAGGTGCGCCGGGCAGCGGACCGCATGAATGGCTAGTACTGACGCCCAAGGACAAAATGCCGCTGCCGGCTGTCGTCTCGTTCCCCAAACCCCCGAAAGCGCCCGATGGCAGCTTGGTGTATGACCGAGTGCCTAACAAGTCACCCGACGTCGTGGCCGTGCCGGCCGACAAGGAGCTCACAATAATTCCCACGCAAGCCACGTCGACGATACGGAAGCGGGCACACGAGGACCAGCAATTGAATGGCACTGAAGTTACTATAGTTCCCAGCGGACCTCCTGCCAAGCGGCCGAATAAGGATCCCATGCCCTCGCATTGTCCCAGTCCTGAGCAGTTTGCGGCCATGATGGCGGCATCTGGACAGCCGCTCTCCAGGCATCATCTCAATGGTAAACAGAAGATTGCGCAGATGGCTCGCGGTGGCAACGGCCGCAAGCAGGTTATCAGTTGGATGGATGCACCGGATGATGTTTACTTTAGGGCTAACGATACACACAAAAAAACGCGAAAAATACTCTCCGCCGTAGATCTGCGTCGCGCCGCGCGCAAACCATGGCGCACACTGCCCATCAAACCTGCGGCGCCCGAGCCGAGTAGCAGGCCCATTGAATCACAAATCGTAATACTGGAC

CDS AA Sequence2

MATNMYRVGDYVYVETTPNSPYLIRRIEELNKNQTGNVEAKVMCFYRRRDLPNPLVQLADKHQPALDEERTSPTQTSGGGGSATGNSGSNSSGTSNNNSSSTAIGGGAGGSGGAGGDAEKGEALTSKQRYQIKHRELFLSRQVESIPATQIRGKCSVTLLNETESLQSYLNKDDTFFYCLVFDPNQKTLLADKGEIRVGSRYQCDIPAKLKDTATDDRKLEELESLVWTPEHSLTDRKIDQFLVVSRSIGTFARALDCSSSVKQPSLHMSAAAASRDITLFHAMNILHKHEYSIEESMSSLVPSTGPVLCRDEIEDWSASEANLFEEALEKYGKDFNDIRQDFLPWKTLKQIIEYYYMWKTTDRYVQQKRVKAVEAELKLKQVYIPQYNNNGKGNGTSTKAGGGIYNGTTNGSTDLSSNGKPCESCGTTKSSQWNSVSSGHSTSRLCLSCWEYWRRYGSMKSATKGDAGEGDAKKKSSSAASTPTATLAGLATTPTAVVDLNDDEKISDLTNRQLHRCSIVNCGKEFKLKTHLARHYAQAHGIAISSGSPRPIMKTRTAFYLHTNPMTRVARAICRSIVKPKKAARQSAYAINAMLVKQEFTNRISGKSQAEIKKLLLLKPKDRGSVTKIANRLGAPGSGPHEWLVLTPKDKMPLPAVVSFPKPPKAPDGSLVYDRVPNKSPDVVAVPADKELTIIPTQATSTIRKRAHEDQQLNGTEVTIVPSGPPAKRPNKDPMPSHCPSPEQFAAMMAASGQPLSRHHLNGKQKIAQMARGGNGRKQVISWMDAPDDVYFRANDTHKKTRKILSAVDLRRAARKPWRTLPIKPAAPEPSSRPIESQIVILD

1   H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
2   Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.