Factors @ Stark Lab

Gene Name Type Activity (log2) in S2 cells
(avg/min/max)
Cluster Data available
S2Kc167BG3OSCHeLa
E2f (FBgn0011766) TF
 
(2.26/-0.09/3.27)

Factor activity

Additional information

E2f [FlyBase] | E2f [FlyMine] | E2f [BDGP]

H. sapiens orthologues1

E2F4 (HGNC:3118, ENSG00000205250), E2F5 (HGNC:3119, ENSG00000133740)

Functionally similar transcription factors and cofactors

CDS DNA Sequence2

ATGTCCAAGTTCTTTGTGAATGTTGCCCCCATCAACAACAGCAACAGCAGCAGTAGCCACACAACCACCAGCAGCAACACCCAGCGCCACCAGCAGCACCAACAACACTATGGCGGGAGCGGGACAACCGGCCACACGATGGTGGCCCGCAGACTCAACTACGATCTGCACGGCGGCACCACCAGCATCAACAACAACAACAACATTGTGATCAAGAACGAGTCCGTCGACTTGGACTACGATCACGTCCTGAGCAGCAGCGACAGCAACAGCAACGGCGGCGTGGCAGCCCACCTGCGGGATCATGTCTACATCAGTCTGGACAAGGGGCACAACACGGGGGCAGTGGCAACAGCAGCGGCGGCGGCAACGGCGGGCCACACGCAGCAGCAACTGCAGCAGCAGCACCACCACCAAAATCAGCAGCAACGCAAGGCGACCGGCAAATCCAACGATATCACAAATTATTACAAGGTCAAACGTCGGCCACACGCCGTCAGCGATGAGATTCACCCGAAGAAGCAGGCCAAGCAGAGCGCCCACCACCAGACGGTGTATCAGAAGCATACGGCTAGCAGTGCGCCCCAGCAGCTCCGGCACAGCCACCACCAGCTGCGCCACGACGCGGATGCCGAACTGGACGAGGATGTGGTGGAGCGGGTGGCCAAGCCGGCATCGCATCACCCCTTTTCGCTGTCGACGCCCCAGCAACAGTTGGCTGCGTCGGTGGCCAGCAGTTCCTCGAGCGGAGATCGCAATCGGGCGGACACCTCGCTGGGAATACTGACCAAAAAGTTTGTGGACCTGCTGCAGGAGTCACCGGATGGCGTGGTGGATCTGAACGAGGCCTCCAATCGATTGCACGTTCAGAAGCGGCGCATCTACGACATTACCAATGTCCTCGAAGGCATTAACATCCTGGAGAAGAAGTCGAAGAACAACATCCAGTGGCGCTGCGGGCAGTCGATGGTCAGCCAGGAGCGTTCCCGTCACATCGAAGCGGATTCGTTGCGGCTGGAGCAACAGGAGAACGAGCTGAACAAGGCCATCGATCTGATGCGCGAGAATCTGGCTGAGATCTCCCAGGAGGTGGAGAACTCCGGCGGCATGGCCTACGTCACGCAGAACGACCTGCTCAACGTGGATCTCTTCAAAGATCAGATCGTTATCGTGATCAAGGCGCCGCCAGAGGCTAAGCTTGTGCTGCCCAACACAAAATTGCCGCGCGAGATTTACGTGAAGGCGGAGAATAGCGGGGAGATCAACGTCTTCCTCTGCCATGACACCTCACCGGAAAATTCGCCAATCGCGCCGGGCGCCGGCTACGTTGGAGCACCCGGTGCAGGATGCGTCCGTACGGCCACCTCCACACGACTGCATCCGTTGACCAACCAGCGACTGAACGATCCGCTCTTCAACAATATCGATGCCATGAGCACCAAGGGATTATTTCAAACGCCCTACCGCTCGGCTCGCAACCTCAGCAAATCGATTGAGGAAGCCGCCAAGCAGTCCCAGCCTGAATATAATAACATTTGTGATATTGCGATGGGCCAGCATCATAATCTGAACCAGCAGCAGCAGCAGCAACAACAACAGTTGCTACAGCAGCCGGAGGAGGACGATGTGGACGTGGAGCTGAACCAGCTGGTTCCGACACTGACGAATCCTGTGGTCCGGACCCATCAGTTCCAGCAGCACCAGCAGCCCTCCATCCAGGAGCTGTTCAGCAGCTTAACAGAATCCTCGCCTCCAACGCCCACCAAGCGGCGTCGGGAGGCAGCAGCCGCAGCAATTGCCGCAGGCAGCTCAACAACAGCAACCACTACGCTTAATAGTCATAACAACAGAAACCACAGCAATCATAGCAACCACAGCAACCATAGCAGCAGCAACAACAGCAAATCCCAACCACCCACAATAGGCTACGGCAGCAGTCAGCGACGCAGCGATGTGCCCATGTATAATTGTGCAATGGAAGGCGCAACCACAACATCTGCAACAGCAGATACGACAGCTGCCACATCGCGATCGGCCGCAGCAAGCTCACTGCAGATGCAATTCGCTGCCGTCGCGGAGAGCAACAACGGCAGTAGCAGCGGCGGTGGTGGCGGCGGCGGCGGCTATGGCAGCATCGCTGGCGCTGGCGCCAACGCTGATCCCCATCAGCCGTACAGCCATGACCGCAACAGCCTGCCGCCCGGCGTGGCTGACTGCGATGCCAACAGCAACAGCAGCAGTGTCACGCTGCAGGGCCTCGATGCTCTCTTCAACGACATTGGCTCGGACTACTTCAGCAACGATATCGCCTTTGTGTCCATCAATCCGCCGGACGACAATGACTATCCGTATGCGCTGAACGCGAACGAGGGCATCGATCGGCTGTTTGACTTCGGTTCGGATGCCTATGGACCC

CDS AA Sequence2

MSKFFVNVAPINNSNSSSSHTTTSSNTQRHQQHQQHYGGSGTTGHTMVARRLNYDLHGGTTSINNNNNIVIKNESVDLDYDHVLSSSDSNSNGGVAAHLRDHVYISLDKGHNTGAVATAAAAATAGHTQQQLQQQHHHQNQQQRKATGKSNDITNYYKVKRRPHAVSDEIHPKKQAKQSAHHQTVYQKHTASSAPQQLRHSHHQLRHDADAELDEDVVERVAKPASHHPFSLSTPQQQLAASVASSSSSGDRNRADTSLGILTKKFVDLLQESPDGVVDLNEASNRLHVQKRRIYDITNVLEGINILEKKSKNNIQWRCGQSMVSQERSRHIEADSLRLEQQENELNKAIDLMRENLAEISQEVENSGGMAYVTQNDLLNVDLFKDQIVIVIKAPPEAKLVLPNTKLPREIYVKAENSGEINVFLCHDTSPENSPIAPGAGYVGAPGAGCVRTATSTRLHPLTNQRLNDPLFNNIDAMSTKGLFQTPYRSARNLSKSIEEAAKQSQPEYNNICDIAMGQHHNLNQQQQQQQQQLLQQPEEDDVDVELNQLVPTLTNPVVRTHQFQQHQQPSIQELFSSLTESSPPTPTKRRREAAAAAIAAGSSTTATTTLNSHNNRNHSNHSNHSNHSSSNNSKSQPPTIGYGSSQRRSDVPMYNCAMEGATTTSATADTTAATSRSAAASSLQMQFAAVAESNNGSSSGGGGGGGGYGSIAGAGANADPHQPYSHDRNSLPPGVADCDANSNSSSVTLQGLDALFNDIGSDYFSNDIAFVSINPPDDNDYPYALNANEGIDRLFDFGSDAYGP

1   H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
2   Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.