Factors @ Stark Lab

Gene Name Type Activity (log2) in S2 cells
(avg/min/max)
Cluster Data available
S2Kc167BG3OSCHeLa
Clk (FBgn0023076) TF
 
(5.55/2.36/7.51)

Factor activity

Additional information

Clk [FlyBase] | Clk [FlyMine] | Clk [BDGP]

H. sapiens orthologues1

CLOCK (HGNC:2082, ENSG00000134852), NPAS2 (HGNC:7895, ENSG00000170485)

Functionally similar transcription factors and cofactors

CDS DNA Sequence2

ATGGACGACGAGAGCGACGACAAGGATGATACAAAAAGGAAATCGCGTAATCTCAGCGAGAAGAAGCGACGAGATCAGTTCAACTCGCTGGTCAACGATCTCAGCGCCTTGATATCCACATCCAGCAGAAAGATGGATAAGTCCACGGTCCTGAAGTCCACGATAGCCTTCCTGAAAAATCATAATGAGGCCACCGATCGCTCCAAGGTTTTCGAAATACAACAGGACTGGAAGCCTGCGTTCCTCAGCAATGACGAATACACTCACCTCATGCTGGAGTCTCTCGATGGTTTTATGATGGTCTTCAGCAGCATGGGCTCCATCTTTTACGCCTCGGAAAGTATTACCTCCCAGCTGGGCTATCTGCCGCAAGATTTGTACAACATGACCATTTATGACCTGGCCTATGAGATGGACCATGAGGCGCTGCTGAATATCTTTATGAATCCCACACCGGTAATCGAGCCCAGACAGACGGACATAAGTTCCAGTAACCAGATCACATTCTACACTCATTTGAGACGCGGCGGGATGGAGAAAGTGGATGCCAATGCCTACGAGTTGGTCAAATTCGTGGGCTACTTTCGTAACGATACCAATACTTCGACGGGTTCCAGTTCGGAGGTTTCGAATGGCTCAAATGGACAACCTGCGGTGCTGCCGCGCATCTTCCAGCAGAATCCCAATGCCGAGGTGGACAAAAAGCTGGTTTTCGTGGGCACTGGACGCGTACAGAATCCCCAACTGATCAGGGAAATGAGCATTATTGATCCCACAAGTAATGAGTTCACTTCGAAACACAGCATGGAGTGGAAGTTTTTGTTTCTGGATCACCGTGCTCCTCCGATCATTGGCTATATGCCCTTCGAGGTTCTGGGGACGTCCGGCTATGATTATTACCACTTTGATGATCTGGACAGTATTGTGGCGTGCCATGAAGAGCTAAGGCAAACGGGTGAGGGCAAGTCTTGCTACTACCGATTCCTTACGAAGGGCCAACAGTGGATATGGTTGCAAACGGACTACTATGTGAGCTATCACCAGTTCAATTCCAAACCAGACTACGTGGTCTGCACCCATAAGGTTGTCAGCTATGCCGAGGTTCTGAAGGATAGTCGAAAGGAGGGCCAAAAATCGGGAAATAGCAACAGCATCACCAACAATGGGAGCAGTAAGGTCATAGCCTCCACGGGAACTAGCAGCAAATCCGCATCTGCCACCACAACACTGAGGGACTTCGAGCTGAGCAGCCAAAATCTGGATAGCACATTGCTCGGAAATAGTCTGGCCAGTTTGGGCACTGAAACAGCAGCCACTTCACCCGCCGTGGACTCGTCGCCCATGTGGTCAGCGTCGGCTGTCCAACCGTCGGGATCATGCCAAATAAATCCCCTGAAGACATCGCGTCCCGCTTCGAGTTATGGCAATATCAGCTCCACAGGAATATCGCCGAAGGCCAAACGAAAGTGCTACTTCTACAACAACCGGGGGAATGACTCGGATTCAACGTCCATGTCGACGGATTCGGTCACCAGCCGGCAGTCCATGATGACGCACGTCAGTTCGCAAAGCCAACGGCAGCGATCGCATCACCGAGAACACCATCGAGAAAATCATCACAATCAGTCACATCATCACATGCAGCAACAGCAGCAGCATCAGAACCAGCAGCAGCAACATCAGCAGCACCAGCAACTGCAACAGCAGCTGCAACATACAGTGGGTACTCCGAAAATGGTGCCTCTCCTGCCGATTGCGTCCACACAAATAATGGCTGGAAATGCGTGTCAGTTTCCCCAACCCGCCTATCCGCTTGCTAGTCCCCAACTGGTGGCACCGACATTTCTTGAGCCGCCGCAATATCTCACCGCCATTCCCATGCAGCCAGTGATCGCTCCGTTTCCGGTGGCGCCAGTGCTTTCCCCACTTCCGGTGCAGTCACAAACGGATATGCTGCCCGATACGGTGGTTATGACGCCAACACAGAGTCAGTTGCAGGATCAATTGCAGCGGAAGCACGACGAACTGCAAAAACTGATCCTCCAGCAACAGAATGAGCTGAGGATCGTATCAGAGCAGCTCCTCCTATCCCGCTACACATATCTGCAGCCCATGATGTCGATGGGATTCGCACCTGGCAACATGACAGCAGCAGCGGTGGGTAATTTGGGAGCCAGTGGCCAACGTGGACTGAATTTCACCGGCAGCAATGCCGTGCAGCCGCAATTCAATCAGTATGGATTTGCACTGAACTCGGAGCAGATGCTTAACCAGCAGGATCAGCAGATGATGATGCAGCAGCAGCAGAATCTGCACACGCAGCACCAGCACAATCTCCAGCAGCAACATCAGAGCCACTCACAGTTGCAGCAACATACCCAGCAGCAACATCAGCAGCAGCAGCAACAACAGCAACAACAGCAGCAACAGCAGCAGCAGCAACAGCAACAACAGCAGCAGCAACAACAGCAGCAACAGCAGCAGCAACAGTTGCAGCTGCAACAACAAAATGATATTTTACTGCGTGAGGATATCGATGATATAGACGCCTTTCTCAATCTGTCCCCCCTGCACTCATTGGGCTCGCAATCCACCATTAATCCCTTCAACTCCAGCAGCAATAACAACAATCAAAGCTACAATGGAGGCAGTAATCTGAATAATGGCAACCAGAACAACAACAATCGCAGTTCAAATCCTCCGCAAAATAATAACGAGGACTCGCTGTTGTCCTGCATGCAGATGGCCACCGAATCGAGTCCTTCGATCAACTTTCACATGGGCATCAGCGATGATGGCTCCGAAACGCAGAGCGAGGACAACAAGATGATGCACACTTCCGGCAGCAATCTGGTGCAGCAGCAACAGCAGCAGCAGCAACAACAACAAATCCTGCAGCAGCATCAACAGCAGTCAAATAGCTTCTTCAGTTCGAATCCCTTTCTCAACAGTCAGAATCAGAATCAAAACCAATTGCCAAACGATCTGGAAATATTGCCATACCAGATGTCCCAAGAGCAATCACAGAATCTATTCAACTCGCCACACACAGCCCCAGGCAGTAGTCAA

CDS AA Sequence2

MDDESDDKDDTKRKSRNLSEKKRRDQFNSLVNDLSALISTSSRKMDKSTVLKSTIAFLKNHNEATDRSKVFEIQQDWKPAFLSNDEYTHLMLESLDGFMMVFSSMGSIFYASESITSQLGYLPQDLYNMTIYDLAYEMDHEALLNIFMNPTPVIEPRQTDISSSNQITFYTHLRRGGMEKVDANAYELVKFVGYFRNDTNTSTGSSSEVSNGSNGQPAVLPRIFQQNPNAEVDKKLVFVGTGRVQNPQLIREMSIIDPTSNEFTSKHSMEWKFLFLDHRAPPIIGYMPFEVLGTSGYDYYHFDDLDSIVACHEELRQTGEGKSCYYRFLTKGQQWIWLQTDYYVSYHQFNSKPDYVVCTHKVVSYAEVLKDSRKEGQKSGNSNSITNNGSSKVIASTGTSSKSASATTTLRDFELSSQNLDSTLLGNSLASLGTETAATSPAVDSSPMWSASAVQPSGSCQINPLKTSRPASSYGNISSTGISPKAKRKCYFYNNRGNDSDSTSMSTDSVTSRQSMMTHVSSQSQRQRSHHREHHRENHHNQSHHHMQQQQQHQNQQQQHQQHQQLQQQLQHTVGTPKMVPLLPIASTQIMAGNACQFPQPAYPLASPQLVAPTFLEPPQYLTAIPMQPVIAPFPVAPVLSPLPVQSQTDMLPDTVVMTPTQSQLQDQLQRKHDELQKLILQQQNELRIVSEQLLLSRYTYLQPMMSMGFAPGNMTAAAVGNLGASGQRGLNFTGSNAVQPQFNQYGFALNSEQMLNQQDQQMMMQQQQNLHTQHQHNLQQQHQSHSQLQQHTQQQHQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQLQLQQQNDILLREDIDDIDAFLNLSPLHSLGSQSTINPFNSSSNNNNQSYNGGSNLNNGNQNNNNRSSNPPQNNNEDSLLSCMQMATESSPSINFHMGISDDGSETQSEDNKMMHTSGSNLVQQQQQQQQQQQILQQHQQQSNSFFSSNPFLNSQNQNQNQLPNDLEILPYQMSQEQSQNLFNSPHTAPGSSQ

1   H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
2   Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.