Factors @ Stark Lab

Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	Data available
Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	S2	Kc167	BG3	OSC	HeLa
Snr1 (FBgn0011715)	cofactor	(-0.41/-3.02/0.05)	4	◼	◻	◻	◻	◻

Factor activity

Celltype:
S2

Additional information

Snr1 [FlyBase] | Snr1 [FlyMine] | Snr1 [BDGP]

H. sapiens orthologues¹

SMARCB1 (HGNC:11103, ENSG00000099956)

Functionally similar transcription factors and cofactors

Similarity:

Euclidean distance

TF	Euclidean distance (rank)
RunxB	1.635 (1)
exd	1.711 (2)
CG11906	1.891 (3)
Crg-1	1.900 (4)
Vsx2	1.941 (5)

All TFs

Cofactor	Euclidean distance (rank)
CG33230	0.970 (1)
Cand1	1.032 (2)
Prosalpha7	1.035 (3)
TfIIA-S-2	1.149 (4)
CG3909	1.235 (5)

All cofactors

Pearson correlation

TF	Pearson correlation (rank)
mor	0.969 (1)
Vsx2	0.903 (2)
Crg-1	0.900 (3)
Met	0.892 (4)
RunxB	0.888 (5)

All TFs.

Cofactor	Pearson correlation (rank)
Cand1	0.977 (1)
Bre1	0.973 (2)
DNApol-delta	0.966 (3)
CG11160	0.965 (4)
CG33230	0.964 (5)

All cofactors.

CDS DNA Sequence²

ATGGCACTGCAGACATACGGGGACAAGCCGGTGGCCTTCCAGCTGGAGGAGGGCGGCGAGTACTACTACGTGGGCTCGGAAGTGGGCAACTACATGCGCCACTTCCGCGGCATTCTGTACAAGAAGTACCCGGGAATGACCCGCATCGTCCTGTCCAACGAGGAGCGCAAGCGGCTGGCTGAGTCCGGCCTCAGCTCCCACATCTTAGCCAGCTCTGTATCGCTGCTCCGCGCCGTAGAGGTGGACGATATCATGGCCGGCAACGATGAAAAGTATCGCGCCGTCTCCGTGAACACTTCCGATACGCCAGTGCCGCGGGAGAGCAAGTCAAAGAAGCAGCCACAGTATGTGCCCACGATGCCGAACTCCAGCCACCTGGACGCAGTGCCACAGGCCACGCCAATCAACCGAAACCGAGTGCACACGAAGAAGGTTCGCACATTCCCGATGTGTTTCGACGACACGGATCCCACGGCTAGCCTGGAGAATGCGGCGCAGAAGGAGTGCCTGGTGCCCATTCGACTGGACATGGAGCTAGAGGGTCAAAAGCTGCGCGACACCTTCACGTGGAACAAGAACGAGAGCATGATTACTCCGGAGCAGTTTGCCGAGGTGCTGTGCGACGACCTGGACCTCAATCCCCTGCCCTTTGTGCCGGCTATTGCACAGGCCATCCGACAGCAGATCGAAGCCTTTCCCAACGATCCCCCCATCCTCGAGGAGACCTGCGACCAGCGGGTCATTGTTAAGCTGAACATTCACGTGGGCAACACCTCGCTCGTCGACCAGGTCGAGTGGGACATGTCCGAGAAGAACAACAACCCCGAGGAGTTTGCCATTAAACTCTGTGCGGAATTGGGATTGGGAGGAGAGTTTGTTACGGCCATTGCCTACAGCATTAGGGGTCAGCTATCGTGGCACTGTCGAACGTACGCCTTCAGCGAGGCCCCTCTATCAACGATTGATGTGCCCTTCCGGAATCCCAGCGACGCTGACGCATGGGCGCCATTCCTAGAGACGCTTACCGACGCCGAAATGGAGAAGAAAATCCGCGACCAGGACCGCAACACGCGCAGAATGCGACGACTGGCCAATACCACAACTGGTTGG

CDS AA Sequence²

MALQTYGDKPVAFQLEEGGEYYYVGSEVGNYMRHFRGILYKKYPGMTRIVLSNEERKRLAESGLSSHILASSVSLLRAVEVDDIMAGNDEKYRAVSVNTSDTPVPRESKSKKQPQYVPTMPNSSHLDAVPQATPINRNRVHTKKVRTFPMCFDDTDPTASLENAAQKECLVPIRLDMELEGQKLRDTFTWNKNESMITPEQFAEVLCDDLDLNPLPFVPAIAQAIRQQIEAFPNDPPILEETCDQRVIVKLNIHVGNTSLVDQVEWDMSEKNNNPEEFAIKLCAELGLGGEFVTAIAYSIRGQLSWHCRTYAFSEAPLSTIDVPFRNPSDADAWAPFLETLTDAEMEKKIRDQDRNTRRMRRLANTTTGW

¹ H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
² Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.