Factors @ Stark Lab

Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	Data available
Gene Name	Type	Activity (log2) in S2 cells (avg/min/max)	Cluster	S2	Kc167	BG3	OSC	HeLa
ken (FBgn0011236)	TF	(-1.03/-3.21/0.03)	13	◼	◻	◻	◻	◻

Factor activity

Celltype:
S2

Additional information

ken [FlyBase] | ken [FlyMine] | ken [BDGP]

H. sapiens orthologues¹

None.

Functionally similar transcription factors and cofactors

Similarity:

Euclidean distance

TF	Euclidean distance (rank)
Su(var)2-10	0.690 (1)
cas	0.856 (2)
CG7839	0.918 (3)
odd	1.049 (4)
h	1.054 (5)

All TFs

Cofactor	Euclidean distance (rank)
CG14220	1.392 (1)
XNP	1.988 (2)
Kdm2	2.006 (3)
CG3815	2.064 (4)
Mi-2	2.233 (5)

All cofactors

Pearson correlation

TF	Pearson correlation (rank)
Su(var)2-10	0.976 (1)
CG8359	0.976 (2)
CG11723	0.960 (3)
CG10669	0.959 (4)
cas	0.958 (5)

All TFs.

Cofactor	Pearson correlation (rank)
CG14220	0.959 (1)
Chrac-16	0.950 (2)
CG43342	0.947 (3)
Su(var)205	0.939 (4)
polybromo	0.903 (5)

All cofactors.

CDS DNA Sequence²

ATGAAAGAGTTTCAAAGAATGTTGATGTTGCAATACAGCAAGCATGGCGAGTGCATACTCAAAGAAATCGGAGCAGCCTTCAGAGGGGAGCACCCGGCGGACCTGACCATCGTCTGCGAGAACAAAGTAAAGCTGCACGCCCACAAGTTGGTCCTGGCGGCCGCCAGTCCGTTGATAAGGAACCTGCTGGAGGACACCCACTTGAGCGACTGCTCCACCACCGTATACTTTCCGGACGTGAATGCCACCTACTTTAAGTTCCTGCTGGACTTCCTGTACTCGGGGCAGACGTGCATTACCTCACGGGATGTGAACTATCTGCACGACCTGCTGCTGCTGCTGCAGATCAAGTCGGACAGCTGGAAGACCACCGACTCCGCCTATCTGAGCAGCAAGTGCGGCGGCCTGCGGGATCGGGCCGACAGGCGGAAGCAGCAGTACACCAGCCCACAGAATTTGGAGCCGGATCAGACGCTCAAGTACGAGGTGGACAGCGTGGATGAGTCGCGCAACGCCGCGGATTTCTCGTCCGCCTTCAACTCCAACGACAATTGCGAGAGTGCGGCCGAGTGCGAGCGGAGTGGTGGCCACAACAACAAGGAGGAGGACGAGGACGACTGCACCCACAAGGACAACAAGAGCGACAAGGACACGGACGAAATTGTAAATCTCTCGAATGCACCGCCCAGCGGCACCAGCGGCAGTAACAGCAACATCAGCACCAGCAGCAACCACCAGCAGCAACAGCACCACCACCATCACCACCACAACCACAACAACAACAATAATAATAACAACAACAACAGCAGCAGCTCAACCATAAATCCCGTCAACCTTTCACTCGACCTTCGGACGAAAAGCGAGAACTCGGCGAGCAGAACCCTGGGATCCGGATCAGACCACAGCGGCATCGACCTGGCAGTGACAGCGAGCGAAAGCACGAAACGGAAGGGCCTGTTCTTCGACTCGCACAAGGATGTGATGAAGCCGCTGTCCGATGGGTCGGACATCAACAGCTCGCCGGAGAACTACGTGGTAACGCCGCATCGGAAGCGGCGACCCGGATTCCACAACACGCAGAGCGACAACCAGCCGTTCACTTCGTACCCACACAGCCTACTGGAGGAACTGCGCTTGGCCAAGTCGACGACGTCGCCCATTTCGGGCTTTGGATCGGAGAAGAACATGCTGGCGCACCTGGAGGACGGAGCACTCAATGGGGACACACTGACGCCGGACAGGAAGCATCTGCTGGAGGCGCAGCGCAATCGAGCCCAGAGTCCCGAGATACCGATGCACTTGGGCCCCCAGTTCGTGTACCAGTGGCAGTCCAACCAGAACGCAGCCATGTCCGCAATGCCCAATCTCCAGTCGCGACTCTCTAGTCTGTCGCACATCAGCCTAAACCTGGATCATCCGGAGGGACGCAGTGGGTCGGCCTCCGGTTCGGGTGCGAACTTGGCCGGCAGCAACACGCACGCCTCCTCGGTCCGGGAGTATCGATGCGAGTACTGTGGCAAACAGTTCGGCATGTCCTGGAACCTCAAGACCCATCTGCGCGTTCACACCGGCGAAAAGCCGTTCGCCTGCCGCCTTTGCGTGGCCATGTTCAAGCAGAAGGCCCACCTGCTGAAGCATCTGTGCTCGGTTCACCGGAACGTCATCACCACCACCAACGGGGCGGATACGGAGAACCGGTACAGCTGCTGCTTCTGCTCCATGTGCTTCGAGTCGGTACAGGAGCTCGTCCGTCACCTGTCCGGCCACCACAATAACCTGCTGCTGACAAAGAATCTGCGCGAA

CDS AA Sequence²

MKEFQRMLMLQYSKHGECILKEIGAAFRGEHPADLTIVCENKVKLHAHKLVLAAASPLIRNLLEDTHLSDCSTTVYFPDVNATYFKFLLDFLYSGQTCITSRDVNYLHDLLLLLQIKSDSWKTTDSAYLSSKCGGLRDRADRRKQQYTSPQNLEPDQTLKYEVDSVDESRNAADFSSAFNSNDNCESAAECERSGGHNNKEEDEDDCTHKDNKSDKDTDEIVNLSNAPPSGTSGSNSNISTSSNHQQQQHHHHHHHNHNNNNNNNNNNSSSSTINPVNLSLDLRTKSENSASRTLGSGSDHSGIDLAVTASESTKRKGLFFDSHKDVMKPLSDGSDINSSPENYVVTPHRKRRPGFHNTQSDNQPFTSYPHSLLEELRLAKSTTSPISGFGSEKNMLAHLEDGALNGDTLTPDRKHLLEAQRNRAQSPEIPMHLGPQFVYQWQSNQNAAMSAMPNLQSRLSSLSHISLNLDHPEGRSGSASGSGANLAGSNTHASSVREYRCEYCGKQFGMSWNLKTHLRVHTGEKPFACRLCVAMFKQKAHLLKHLCSVHRNVITTTNGADTENRYSCCFCSMCFESVQELVRHLSGHHNNLLLTKNLRE

¹ H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
² Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.