Factors @ Stark Lab

Gene Name Type Activity (log2) in S2 cells
(avg/min/max)
Cluster Data available
S2Kc167BG3OSCHeLa
lid (FBgn0031759) cofactor
 
(-0.64/-1.05/-0.07)

Factor activity

Additional information

lid [FlyBase] | lid [FlyMine] | lid [BDGP]

H. sapiens orthologues1

KDM5A (HGNC:9886, ENSG00000073614), KDM5B (HGNC:18039, ENSG00000117139), KDM5D (HGNC:11115, ENSG00000012817), KDM5C (HGNC:11114, ENSG00000126012)

Functionally similar transcription factors and cofactors

CDS DNA Sequence2

ATGTCCGCCAAAACCGAGGCGGACAACACGACGGCCGCCAACTCCGGCGGCGGAGGAGTCGGGAGCGGCACCTCATCCGGCGGGGGCGCATCCGCGAATGGAACAGCAACTCCGGCACGTCGTCTGCGTACCCGAAACTCAACGGGCAACGGGACTAATAGTGGAAGTGAGTCCGTAAAGAAATCCAATGCTAACGACGAGCCCTCGACCCCAGTCACCCCGGCAGGAGCAACAGGATCTCACACCCATGCTCCGCCAGGCATTTCTCCGGCGGTAATGGAACGGCCTATGCCCAGTGTTCCCATGAATCACGCCAGCAGCAGTGTGTCAGCCAGCAAAAAGTACCATAATAGTTGTCCTCATCCCACACCCACGCCTGCGCCCACTGGGCACAAGAAGTCGGTCCACACGCAGCCGCACAGCAGCAACAAGTTTGACCAGGGAAAGAACGAGGAGTTCCACTTTGACACGCCGCCAGAGTGCCCTGTGTTCCGGCCCACAACTGAGGAGTTCAAGAATCCACTGGCCTACATCAGCAAGATCCGCTCCATAGCTGAGAAGTGTGGAATCGCAAAGATCCTGCCGCCGGCAACCTGGTCGCCGCCGTTTGCAGTGGACGTGGACAAGCTACGCTTTGTGCCACGTGTCCAGCGGCTGAATGAGCTCGAGGCAAAGACGCGCGTCAAACTCAACTTCCTTGATCAGATCGCAAAGTTCTGGGAGCTGCAAGGCTCTTCACTAAAGATCCCAATGGTGGAGCGAAAGGCTCTCGACTTGTACACACTGCACCGCATCGTTCAGGAGGAGGGGGGCATGGAGCAAACCACAAAGGATCGCAAGTGGGCCAAGGTGGCCAACCGGATGCAGTACCCCTCAAGCAAAAGTGTTGGCGCAACCCTGAAGGCACACTACGAACGCATCTTGCACCCCTTTGAGGTATACACTTCGGGAAAGGTTCTAGGACCCACACCAACGTCGTCTGGATCTGGTAGCACACCCGTTAAATTGGAGGACGGAGGTGGAACCGACTACAAAGCCCATGAAATTCCCACACGGCAGCAGATTGTGCCGCCCAACGAGACAAACACACGTCGCTCCAAGCGTTTCGGAAATTCCAATGCCAGCTGCGGCCTGAGTGGTGTTACACCCACAACAAAGCCATCAGCGGGCGTATTTGTCAAGACGGAGAACAAGGAAGAATTTAAGAGGGATCTTCTCAGCAGTTTCAATGCTGTCAACAGCGGCGGATCGCCATTAGCCACAGGTACTACGGCAAACACTCGCGGAGCCAGCCAGAAGAAGGGAGGAGAGCCTCCAGCACTTATCGTAGACCCACTGATGAAGTACATTTGCCACATCTGCAATCGCGGCGACGTCGAGGAGTCAATGCTGCTTTGCGATGGCTGCGACGACAGCTACCACACCTTTTGCCTGTTGCCGCCTCTGACCAGCATACCCAAAGGCGAATGGCTTTGCCCGCGCTGCGTCGTCGAGGAAGTAAGCAAACCGCAGGAGGCGTTCGGTTTTGAGCAGGCGGAGAGGGAATACACTCTGCAACAATTTGGACAAATGGCTGACCAGTTCAAGCAAGAATACTTCCGCAAGCCGGTGCACTTGGTGCCCACTGAGATGGTGGAGCGCGAGTTTTGGCGCATCGTGTCATCTATCGATGAAGACGTTACCGTTGAGTATGGGGCGGACTTGCACACAATGGATCACGGCTCTGGTTTTCCCACTAAGAGCTCGTTATATTTGTTGCCGGGCGACCAAGAGTATGCAGAGTCAAGCTGGAACCTTAACAACTTGCCGTTGCTGGAGGATTCCATTCTTGGTCACATCAATGCCGACATTAGCGGCATGAACGCTCCGTGGATGTATGTGGGCATGTGCTTCGCAGCCTTCTGCTGGCACAACGAGGACCACTGGAGCTACTCCATCAACTATCTTCACTGGGGAGAACCTAAAACCTGGTACGGTGTTCCGGGGTCCTGTGCTGAGCAGTTTGAAGAGACCATGAAGCAGGCAGCTCCAGAACTTTTTTCATCACAGCCCGATCTGCTTCACCAGCTGGTGACCATTATGAACCCGAACATTTTGATGAACAATCGTGTACCGGTATTCCGAACCGATCAGCATGCAGGCGAGTTTGTGATCACCTTTCCCAGGGCCTATCACGCAGGCTTTAACCAAGGCTATAACTTCGCGGAGGCCGTCAATTTTGCACCTGCCGATTGGCTGAAGATGGGGCGCGAGTGTGTTAACCACTATTCCATGCTGCGACGTTTCTGTGTCTTTTCGCACGATGAGCTCGTTTGCAAGATGGCCCTGGAGCCAGCGAAACTCACATTTGGCATCGCTACTGCCTGCTACATCGACATGGCCGAAATGGTCGACACAGAGAAGAAACTGCGCAAATCGCTTTTGGAGTGGGGCGTTACCCGCGCAGAGTGTCGCGCCTTCGAGCTAGTGAACGACGATGAGCGCCATTGCCAAGAGTGCAACACCACGTGCTTCCTGTCGGCGGTGACCTGCGAGTGCAACGACAAGTTGATTGTCTGTTTGCGCCACTACACGGTACTCTGCGGCTGTGCTCCTGAGAAGCACACTCTGATATATCGTTATACACTGGACGAGATGCCGCTGATGCTGCAGAAACTTAAGGTGAAGGCGCACAGCTTCGAGCGATGGCTTTCACGTTGCCGTGACATAGTCGATGCACATACACCCACCTCGGTGACCCTGCAGGAGCTGCAGGAATTGTGCAAGGAGGCCGAGACGAAAAAGTTTCCCTCATCGCTGCTCATCGATCGCCTTAATGCTGCGGCCGTTGAGGCAGAGAAATGTGTCACAGTCATACAGCAACTGGGTATCAATAAGGTGCGAACTCGCTCGGACCACAACCAGGAGGCTGCTCAGTACAAGCTAACCATGGAGGAGCTAGAGTTGTTCGTTCAAGAAATCGATAATCTCTGCTGCATCATTGACGAGGGCGCTTCGGTGCGAGAGCTGCTTGTTTTGGGAAAACAGTTTGTGGAGCGGTCCGAGAGCCAGCTGCAATTATCGCTGGAGTCTCTGGAGGAGAGTGAGCTGGAAACGTTAATAAACGAAGGCAGCTCCTTACGCATCGAACTGCAACAGCTCGACCTACTGCAAAAGCGACTGAAGCAGTGCAAGTGGTACAAGCGCTCGCAGGGATTGAGGGAGACCAGCTCGAAGCTGACCTACCAAGACGTGAAGAACCTGTTACACATTGCGGCTGCTGACCTTGATCCCACGGATCCGTATGTCGACAAGGAGATGCGAAAATTGCAACAGATCGGTGCAGATATCGAAGCCTGGGAGTCGCAGGCGGCCAAGTATTTCCGGCGACTGACCCAACAGCACGAACTGGGCGAAATTGAGCAGTTCTTGAAATCGGCCTCCGACATCAACGGTCAAGTGCCTTCGCATGGACTGCTGAAGGATGCACTACGAAAGGCGCGTGAGTGGCTACGGGCCGTTGAGCAGCTACAGCAAAACAACCACGTCACATATTGCCACACACTGGAGGCAATGATCGAGCGCGGCTTGAACATACCCATCCAGCTGGAGGAGCTGAGCCGAATGCAGGGACACCTAAATAGTGCACATCAATGGAAGGACAATACAGCGTGCGCCTTCCTCAAGAAGGGCACCTTCTATACGCTCTTGGAGGTTCTCATGCCCCGGTCGGACGCCATCAACATAGACTCGGATCTCAAGCCGCGCTTCCAGGATGATTTTCTGAAAGAGAAAAATCCGGCGGAGATTGTGGCCAGCTTCAAGCACGCTGAGGAGCAGGAGCTGCTCGATATGCGCGAACTTCGGCGGCAAAATATGAACAAGAATCCCATGCGCGATATGTTCTGCTTGTGCAAGTCCGAGTTCCGAAACTTAATGTTCAATTGTCAGTTGTGCCGCGATTGGTTTCACGAGGATTGCGTCCCACCGCCATCAGCCACAAATCAAAATGGAATTGTTAACGGCGGATCAGGACCAGGTACCAATCGACCCAAGTGGCTATGTCCGAGCTGTGTGCGCTCGAAGAGACCGCGCCTAGAAACCATCCTTCCGCTACTTGTCCAGCTGCAGCAACTGCCCATCCGTCTGCCCGAGGACGAAGCGTTGCGTTGCCTGGCGGAGCGTGCGATGAACTGGCAGGATCGGGCCAGGAAAGCTCTTAGCAGTCCTGACGTCAGTGCGGCTCAAGAAGCGATTATGGCGCAGCAGCAGCAGAAGCGGCGCTCCGAGGGTGGAGCAGGGGTGGGAAATATCAGCAGTCCACGGAAGCCACGTCGACGGGGGAGCCTGACGAAAGAGGCAAGTGGTTCAACAGAGTCCGATGCCGACGACGATGACGACGAGGACGAATGTCGTCTTCGAATCGTCGAAGACAACTTTAGTAACGATGAAGATGAGCCTCGTACCGCCCCCGCGACCTCCACCGTCAACTCCGATCTCCTCAAGCTGCTGTCCGACAGTGAAATTGAAAATTTGCTTGACCTGATGATGGAGGGCGACCTGCTAGAGGTATCCTTAGATGAAACGCAGGAGCTGTGGCGCATTCTAGAAACGATGCCGCCCACGTTGCTGCAGGCGGAGGCCATGGAGCGTGTTGTCCAGCACATGCAGCGTCAGCGGCAACAGCATACAAATCCGCTGCCAACATCCGGCGCCGAAGACTCTAACGATAGTCTGATGGTACAAAATAGTCCCAATAGCAACAGCAATAGTGGCGGGGCAACGGGTTCTGCGAGCAACAGCGGACGCAACAAGAAGAGGCGCTCCAACGACACCGGCGGCAACTCGGCAGTGCCGCGCAAGAAGCAGAGCACACCGAAGCAGACACCGGGCAAGAAGGGATCAGCGGCAGCGGCACGCAAGAGCGATGCCAAGGCATCGCCAGCAGCATCCACCACTCCGGGTGCGGATGCCGATGCCGAGAATAAGCAGGCCAACGGCGGTAATACGAACTCCAGTACAGGATCAGGTGGTGGAAATTCTGCGACGACGACGCCCACACCCGGCTCGACGCACAAAAAGCGAAAGCGCACCTCAACCACAGCCACCAATAATAACAACAACAATAATAATAACAGCACGAACAATAGCAACAGCAGTACCAATTTGAACAGCAACACCACCAGCGGCCAGGGAGCAGCCACTGGAGGCAATAATGCGACTGGCGGTCAGAAGAAGCACGCGCAACGGTCTCAACAGGCGGCGCAGGAGGACGACGAGGAGGAGTGCCGGGCGGAGAACTGCCACAAGCCAACCGGGCGAGAGGTGGACTGGGTGCAGTGCGACGGCGGCTGCAACGAATGGTTCCACATGTACTGTGTGGGCCTCAATCGCAGCCAGATAAAGCCCGACGACGACTATATCTGCATTCGATGCACAAAGACAGTTGCCATCGGAACACAGGGCTCCGGTCACAGTATGAGCGTGGCGTCCACGACGACGCCGGGCAAGCAGCGGGCGGTGCAATCGGCGCGG

CDS AA Sequence2

MSAKTEADNTTAANSGGGGVGSGTSSGGGASANGTATPARRLRTRNSTGNGTNSGSESVKKSNANDEPSTPVTPAGATGSHTHAPPGISPAVMERPMPSVPMNHASSSVSASKKYHNSCPHPTPTPAPTGHKKSVHTQPHSSNKFDQGKNEEFHFDTPPECPVFRPTTEEFKNPLAYISKIRSIAEKCGIAKILPPATWSPPFAVDVDKLRFVPRVQRLNELEAKTRVKLNFLDQIAKFWELQGSSLKIPMVERKALDLYTLHRIVQEEGGMEQTTKDRKWAKVANRMQYPSSKSVGATLKAHYERILHPFEVYTSGKVLGPTPTSSGSGSTPVKLEDGGGTDYKAHEIPTRQQIVPPNETNTRRSKRFGNSNASCGLSGVTPTTKPSAGVFVKTENKEEFKRDLLSSFNAVNSGGSPLATGTTANTRGASQKKGGEPPALIVDPLMKYICHICNRGDVEESMLLCDGCDDSYHTFCLLPPLTSIPKGEWLCPRCVVEEVSKPQEAFGFEQAEREYTLQQFGQMADQFKQEYFRKPVHLVPTEMVEREFWRIVSSIDEDVTVEYGADLHTMDHGSGFPTKSSLYLLPGDQEYAESSWNLNNLPLLEDSILGHINADISGMNAPWMYVGMCFAAFCWHNEDHWSYSINYLHWGEPKTWYGVPGSCAEQFEETMKQAAPELFSSQPDLLHQLVTIMNPNILMNNRVPVFRTDQHAGEFVITFPRAYHAGFNQGYNFAEAVNFAPADWLKMGRECVNHYSMLRRFCVFSHDELVCKMALEPAKLTFGIATACYIDMAEMVDTEKKLRKSLLEWGVTRAECRAFELVNDDERHCQECNTTCFLSAVTCECNDKLIVCLRHYTVLCGCAPEKHTLIYRYTLDEMPLMLQKLKVKAHSFERWLSRCRDIVDAHTPTSVTLQELQELCKEAETKKFPSSLLIDRLNAAAVEAEKCVTVIQQLGINKVRTRSDHNQEAAQYKLTMEELELFVQEIDNLCCIIDEGASVRELLVLGKQFVERSESQLQLSLESLEESELETLINEGSSLRIELQQLDLLQKRLKQCKWYKRSQGLRETSSKLTYQDVKNLLHIAAADLDPTDPYVDKEMRKLQQIGADIEAWESQAAKYFRRLTQQHELGEIEQFLKSASDINGQVPSHGLLKDALRKAREWLRAVEQLQQNNHVTYCHTLEAMIERGLNIPIQLEELSRMQGHLNSAHQWKDNTACAFLKKGTFYTLLEVLMPRSDAINIDSDLKPRFQDDFLKEKNPAEIVASFKHAEEQELLDMRELRRQNMNKNPMRDMFCLCKSEFRNLMFNCQLCRDWFHEDCVPPPSATNQNGIVNGGSGPGTNRPKWLCPSCVRSKRPRLETILPLLVQLQQLPIRLPEDEALRCLAERAMNWQDRARKALSSPDVSAAQEAIMAQQQQKRRSEGGAGVGNISSPRKPRRRGSLTKEASGSTESDADDDDDEDECRLRIVEDNFSNDEDEPRTAPATSTVNSDLLKLLSDSEIENLLDLMMEGDLLEVSLDETQELWRILETMPPTLLQAEAMERVVQHMQRQRQQHTNPLPTSGAEDSNDSLMVQNSPNSNSNSGGATGSASNSGRNKKRRSNDTGGNSAVPRKKQSTPKQTPGKKGSAAAARKSDAKASPAASTTPGADADAENKQANGGNTNSSTGSGGGNSATTTPTPGSTHKKRKRTSTTATNNNNNNNNNSTNNSNSSTNLNSNTTSGQGAATGGNNATGGQKKHAQRSQQAAQEDDEEECRAENCHKPTGREVDWVQCDGGCNEWFHMYCVGLNRSQIKPDDDYICIRCTKTVAIGTQGSGHSMSVASTTTPGKQRAVQSAR

1   H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
2   Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.