Factors @ Stark Lab

Gene Name Type Activity (log2) in S2 cells
(avg/min/max)
Cluster Data available
S2Kc167BG3OSCHeLa
Actn (FBgn0000667) cofactor
 
(-0.55/-2.09/0.08)

Factor activity

Additional information

Actn [FlyBase] | Actn [FlyMine] | Actn [BDGP]

H. sapiens orthologues1

ACTN1 (HGNC:163, ENSG00000072110), ACTN4 (HGNC:166, ENSG00000130402), ACTN2 (HGNC:164, ENSG00000077522), ACTN3 (HGNC:165, ENSG00000248746)

Functionally similar transcription factors and cofactors

CDS DNA Sequence2

ATGATGATGGAGAACGGACTCTCCATGGAGTACGGAGATGGCTACATGGAGCAGGAGGAGGAGTGGGAGCGCGAGGGCCTGCTCGATCCTGCGTGGGAGAAGCAACAGAAGAAGACATTTACCGCCTGGTGTAACAGCCATTTGCGCAAGGCCGGTACAGCCATCGACAACATCGAGGAGGACTTCCGCAACGGCCTCAAGCTGATGCTGCTGCTGGAGGTGATCTCCGGCGAGACGCTCCCCAAGCCCGATCGCGGCAAGATGCGCTTCCACAAGATCGCCAACGTGAACAAGGCTCTCGACTTCATCGCCTCCAAGGGCGTCCACCTGGTCTCTATCGGCGCCGAGGAGATCGTCGATGGAAACTTGAAGATGACTCTGGGTATGATCTGGACGATTATCCTGCGCTTCGCCATTCAGGACATCTCCGTGGAGGAGATGACCGCCAAGGAGGGTCTGCTGCTGTGGTGCCAGCGCAAGACGGCTCCCTACAAGAACGTCAACGTACAGAACTTCCATCTGTCGTTCAAGGATGGTCTGGCCTTCTGCGCCCTTATCCATCGCCATCGTCCAGATCTAATCGACTACGCCAAGCTGTCCAAAGACAATCCTCTGGAGAATCTTAATACTGCCTTCGATGTGGCCGAGAAGTACCTGGATATTCCGCGCATGTTGGATCCAGATGATCTCCAGAATACAGCTTTGCCCGATGAGCGGGCGGTGATGACGTATGTGTCCTCGTACTATCACTGCTTCAGTGGCGCCCAAAAGGCGGAAACCGCTGCCAACCGGATCTGCAAGGTGCTCAAGGTCAACCAGGAGAACGAACGCCTCATGGAGGAGTACGAGCGTCTGGCCAGTGATTTGCTGGAGTGGATCCGTCGCACCATGCCCTGGTTGAACTCGCGCCAGGCCGACAACTCGCTGGCAGGTGTGCAGAAGAAGCTGGAGGAGTACCGCACCTACCGTCGCAAGCACAAGCCACCACGTGTGGAGCAGAAGGCCAAGCTGGAGACCAACTTCAACACGCTGCAGACCAAGCTGCGCCTGTCCAACCGGCCCGCCTACCTGCCCACCGAGGGCAAGACCGTGTCCGACATCTCCAACTCGTGGAAGGGCCTGGAGCTGGCCGAGAAGGCCTTTGAGGAATGGCTGCTGGCCGAGACCATGCGCCTGGAGCGCCTTGAACATCTGGCCCAGAAGTTCAAGCACAAGGCCGATGCCCACGAGGACTGGACGCGTGGCAAGGAGGAGATGCTGCAGTCGCAGGACTTCCGCCAGTGCAAGCTCAACGAGCTGAAGGCCCTAAAGAAGAAGCACGAAGCCTTTGAGTCTGACCTGGCCGCCCACCAGGATCGTGTGGAGCAGATTGCCGCCATCGCCCAGGAGCTTAACACTCTGGAGTACCATGACTGTGTGTCTGTGAACGCCAGGTGCCAGCGCATCTGCGACCAATGGGATCGCTTGGGTGCTCTTACCCAGCGCAGGCGCACCGCCTTAGACGAGGCCGAGCGAATCCTGGAGAAGATCGACATCTTGCATTTGGAGTTCGCGAAGCGTGCGGCGCCGTTCAACAACTGGCTGGATGGTACGCGCGAGGATCTTGTGGACATGTTTATTGTACACACCATGGAGGAAATCCAAGGCCTGATCCAGGCGCACGACCAGTTCAAGGCGACCCTGGGTGAGGCCGACAAGGAGTTCAACCTGATCGTGAACCTGGTCCGCGAAGTGGAGTCGATTGTGAAGCAGCACCAGATCCCCGGCGGCCTAGAGAACCCCTACACCACCCTGACCGCCAACGACATGACGCGCAAGTGGAGCGACGTCCGCCAACTGGTGCCCCAACGCGACCAGACTTTGGCCAACGAGCTGCGCAAGCAACAGAACAACGAAATGCTCCGCCGTCAGTTTGCCGAGAAGGCCAACATTGTCGGCCCCTGGATCGAGCGGCAAATGGATGCTGTTACGGCCATCGGTATGGGACTGCAGGGATCGCTGGAGGACCAACTGCACCGGCTCAAGGAGTACGAGCAGGCCGTCTACGCCTACAAGCCGAACATTGAGGAGCTGGAGAAGATCCACCAAGCGGTGCAGGAATCGATGATCTTCGAGAACCGATACACCAACTACACGATGGAAACGCTGCGCGTCGGCTGGGAGCAGCTGCTTACATCTATCAACCGCAACATCAACGAGGTGGAGAACCAGATTCTCACCCGCGACTCCAAGGGCATTAGCCAGGAGCAGCTGAACGAATTCCGCAGCAGCTTCAACCACTTCGACAAGAACCGCACCGGCCGACTGTCGCCCGAGGAGTTCAAGTCGTGCTTGGTCTCGTTGGGCTACTCGATTGGCAAGGATCGCCAGGGTGATTTGGACTTCCAGCGCATCCTCGCCGTCGTCGATCCCAACAACACTGGCTACGTGCACTTCGACGCCTTCCTCGACTTCATGACCCGCGAGAGCACCGATACCGACACTGCCGAACAAGTCATCGACTCCTTCCGAATCCTGGCAGCCGACAAGCCATACATTTTGCCCGACGAACTGCGTCGCGAGTTGCCGCCAGACCAGGCCGAGTACTGCATCCAGCGCATGCCGCCCTATAAGGGACCCAACGGAGTGCCCGGCGCCCTGGACTACATGTCCTTCAGCACAGCTCTCTACGGCGAGACCGACTTG

CDS AA Sequence2

MMMENGLSMEYGDGYMEQEEEWEREGLLDPAWEKQQKKTFTAWCNSHLRKAGTAIDNIEEDFRNGLKLMLLLEVISGETLPKPDRGKMRFHKIANVNKALDFIASKGVHLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISVEEMTAKEGLLLWCQRKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPDLIDYAKLSKDNPLENLNTAFDVAEKYLDIPRMLDPDDLQNTALPDERAVMTYVSSYYHCFSGAQKAETAANRICKVLKVNQENERLMEEYERLASDLLEWIRRTMPWLNSRQADNSLAGVQKKLEEYRTYRRKHKPPRVEQKAKLETNFNTLQTKLRLSNRPAYLPTEGKTVSDISNSWKGLELAEKAFEEWLLAETMRLERLEHLAQKFKHKADAHEDWTRGKEEMLQSQDFRQCKLNELKALKKKHEAFESDLAAHQDRVEQIAAIAQELNTLEYHDCVSVNARCQRICDQWDRLGALTQRRRTALDEAERILEKIDILHLEFAKRAAPFNNWLDGTREDLVDMFIVHTMEEIQGLIQAHDQFKATLGEADKEFNLIVNLVREVESIVKQHQIPGGLENPYTTLTANDMTRKWSDVRQLVPQRDQTLANELRKQQNNEMLRRQFAEKANIVGPWIERQMDAVTAIGMGLQGSLEDQLHRLKEYEQAVYAYKPNIEELEKIHQAVQESMIFENRYTNYTMETLRVGWEQLLTSINRNINEVENQILTRDSKGISQEQLNEFRSSFNHFDKNRTGRLSPEEFKSCLVSLGYSIGKDRQGDLDFQRILAVVDPNNTGYVHFDAFLDFMTRESTDTDTAEQVIDSFRILAADKPYILPDELRRELPPDQAEYCIQRMPPYKGPNGVPGALDYMSFSTALYGETDL

1   H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
2   Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.