Factors @ Stark Lab

Gene Name Type Activity (log2) in S2 cells
(avg/min/max)
Cluster Data available
S2Kc167BG3OSCHeLa
Mad (FBgn0011648) TF
 
(-0.35/-2.17/0.24)

Factor activity

Additional information

Mad [FlyBase] | Mad [FlyMine] | Mad [BDGP]

H. sapiens orthologues1

SMAD1 (HGNC:6767, ENSG00000170365), SMAD5 (HGNC:6771, ENSG00000113658), SMAD9 (HGNC:6774, ENSG00000120693)

Functionally similar transcription factors and cofactors

CDS DNA Sequence2

ATGGACACCGACGATGTGGAATCGAACACAAGCAGCGCGATGTCCACACTGGGCTCGCTATTCTCCTTCACATCGCCGGCGGTGAAGAAGCTGCTGGGCTGGAAACAGGGTGACGAAGAGGAGAAGTGGGCGGAGAAGGCCGTCGACAGTCTGGTGAAGAAGTTGAAGAAGCGCAAGGGCGCCATCGAGGAGCTGGAGCGTGCGCTCTCCTGTCCCGGTCAGCCCTCGAAGTGTGTCACCATTCCACGCTCGCTGGACGGACGATTACAGGTCTCCCATCGCAAGGGTCTGCCGCATGTGATCTACTGCCGCGTGTGGCGCTGGCCAGATCTGCAGTCGCACCACGAACTGAAGCCACTCGAGCTGTGCCAGTATCCGTTCAGCGCCAAGCAGAAGGAGGTGTGCATCAATCCGTATCACTATAAGCGCGTGGAGAGTCCGGTGCTCCCGCCAGTACTCGTTCCTCGCCACTCGGAATTCGCGCCCGGTCACTCGATGCTGCAGTTCAACCATGTGGCCGAGCCCAGTATGCCGCACAATGTGAGCTACTCGAACAGTGGATTCAACTCGCACAGCTTGAGCACCAGCAACACATCGGTGGGCAGTCCGAGTTCCGTCAACTCCAATCCCAATTCGCCGTACGACAGCTTGGCGGGAACACCGCCACCCGCCTACAGTCCCTCGGAGGATGGCAACTCCAACAATCCGAACGACGGTGGCCAGCTGCTGGATGCTCAGATGGGCGATGTTGCCCAGGTTAGCTATTCGGAGCCCGCCTTCTGGGCGTCGATAGCCTACTACGAGCTAAATTGCCGCGTGGGCGAGGTGTTCCACTGCAACAACAACTCCGTGATCGTTGACGGTTTCACGAATCCTTCCAACAACTCGGACCGCTGCTGTCTCGGCCAGCTGAGCAACGTGAACAGGAATAGCACCATCGAGAACACACGCCGTCATATAGGCAAGGGTGTTCATTTATACTATGTGACCGGCGAGGTCTACGCCGAATGCCTATCCGACTCCGCCATTTTCGTGCAGTCGCGCAACTGCAACTACCACCACGGATTCCATCCGAGCACCGTGTGCAAAATACCGCCGGGCTGCTCGCTGAAGATCTTCAACAATCAGGAATTTGCTCAGCTGCTGTCGCAGTCGGTGAACAATGGATTCGAGGCCGTCTACGAGCTGACAAAGATGTGCACGATCCGGATGTCGTTCGTGAAGGGCTGGGGTGCGGAGTATCATCGCCAGGATGTGACCTCGACGCCCTGTTGGATTGAAATCCATCTGCACGGGCCGCTCCAGTGGCTGGACAAGGTGCTCACCCAAATGGGCTCTCCGCATAATGCAATTAGTTCGGTATCC

CDS AA Sequence2

MDTDDVESNTSSAMSTLGSLFSFTSPAVKKLLGWKQGDEEEKWAEKAVDSLVKKLKKRKGAIEELERALSCPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLELCQYPFSAKQKEVCINPYHYKRVESPVLPPVLVPRHSEFAPGHSMLQFNHVAEPSMPHNVSYSNSGFNSHSLSTSNTSVGSPSSVNSNPNSPYDSLAGTPPPAYSPSEDGNSNNPNDGGQLLDAQMGDVAQVSYSEPAFWASIAYYELNCRVGEVFHCNNNSVIVDGFTNPSNNSDRCCLGQLSNVNRNSTIENTRRHIGKGVHLYYVTGEVYAECLSDSAIFVQSRNCNYHHGFHPSTVCKIPPGCSLKIFNNQEFAQLLSQSVNNGFEAVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNAISSVS

1   H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
2   Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.