Factors @ Stark Lab

Gene Name Type Activity (log2) in S2 cells
(avg/min/max)
Cluster Data available
S2Kc167BG3OSCHeLa
JIL-1 (FBgn0020412) cofactor
 
(-0.52/-3.27/0.18)

Factor activity

Additional information

JIL-1 [FlyBase] | JIL-1 [FlyMine] | JIL-1 [BDGP]

H. sapiens orthologues1

RPS6KA5 (HGNC:10434, ENSG00000100784), RPS6KA4 (HGNC:10433, ENSG00000162302)

Functionally similar transcription factors and cofactors

CDS DNA Sequence2

ATGAGTCGCTTGCAAAAGCAAAACTACGAGATCTTAAGCGGTACAAGTACGTCGCGCCTCAAGAATCATCAACATCCCCGTGAATCGGAGTCACTAGCCTACGAGGAGCCAGATCAAATGGTGCGGAATCATCTAAATGGCCAGCTGGTAGCCAATGGCAATGGCAAAACGCGAAAGAATAGCAATTCCGAAACGATGACCAATGGGAAAAAGTCCAAACTGAATACGGAGGGATCCGGCTCTGGTTCTGGAAAGACCTTGAACTACAATAATAATAACAATAACAACAACAGCATCAGTGCCACCAACGGTCAGTACACCAATAGCAGCAGCAAGACCACTTCAGCATCTGCAAGGGATTACACTTACCGCGAGACCATATCACCGCCCACACCTCCATCCCCGCCCACCACAAATGTGGCGGATATTGTTTGCATATCGGATGCGGAGAGCGAGGACGGACGCGATCCCGAGCGGGAGTACTACGACCAGGACATGGAGGAGGATGAGCCGAACGGGATAGAGATCGATGAATCCAGCTCCAGCTTGTCCAAGGCCAAGTCCAACAATGCAGCTGCAGCAGCGGCGGCGGCGGCTGCAGCAGCGGCAGCAGCAGCCTCGAAGGCCTCCTCGTCGACCACGCCCTCCTACGCCATGCCCACCAGCAATAGTACACCCCTTGATCTGGACAATGAGGCCCATCAACGGGACCTGGAGGCGGTCACCGATCTGAAATACTACGTAAAATTGTACAGTGATGAGGCCGTTAGTCTGAATGACTTCAAAATAATACGCGTTCTCGGAACAGGTGCCTATGGGCGGGTTTTCCTCGTTCGCAAGCTAACTAGACACGATGCCGGAAAATTGTATGCAATGAAGGTTCTCAATAAGATAACGGTGGTCCAGAAGCGAAAAACCGCGGAACACACCAAAACGGAGAGAGTGGTACTGGAGGCCATTCAACGTAATCCCTTCCTCGTGAGTCTACACTACGCCTTCCAATCCTCATCAAAGCTTTACCTCGTGCTAGACTTTGCCAATGGCGGTGAGCTCTTCACGCATCTCTACCACTCTGAGAACTTTGAGGAGTCCCGGGTGCGTGTGTACATAGCCGAGGTGGTGCTGGCCCTGGAGCAACTGCATCAGTTGGGGATCATCTATCGAGATATTAAGTTGGAGAATATTTTGCTTGATGGCGAGGGGCACATTGTTCTGTCCGACTTTGGACTGTCGAAGATCCTTACCGCGGAGAATGAATACCGTGCGCATAGCTTCTGCGGCACTCTGGAGTATATGGCACCTGAGATAATCCGTACGGGGCCGCCAGGACACGACAGTGCCGTGGACTGGTGGTCGGTGGGTGTGCTCACTTTTGAGCTGCTCACCGGCGCTTCGCCATTCGCCACGTCCGACGGCCAGGTCCAGCAATCGGAAATCTCGCGGCGGATTCAGAAGGAGCAGCCAATGATTCCCTCATCGTTCAGTGCCAACGCCCGCGACTTTGTGCTAAAGATGTTGGAAAAGAATCCAAAGCGGCGCTTGGGTGGCAACCATCGCGACGCCAGCGAAATCAAGGAGCACCCCTTCTTCAACGGCATTAACTGGCAGGAGTTGCGGACAAAGCGCCGCAAAGCCCCCTATAAGCCCACCCTCACCGCCGAGGACGATGTGCAGAACTTCAGCAACGAGTTTACCGACCAAGTGCCCGAGGATCCCGAGTGCGATGCTCCGCCCAGCCGGATACGACTATTTCGCGGTTACACATACGTGGCGCCAGAGCATTTGGAGCAGATGCGAAGGGATAACCACTGTGAGATTCAATACTTTAATACAGGACTTCAGAATATACCTTGTCGGCCAGATGATCTTGAATTGGGCACACGCACTTCAAACGGAGCCTATGGCACATGCCATTTTGTGGTGGACAGCTCTACGGATTTGGTGTTTTTGGCCAAAATAATACCGCTATCCAAGTTCCGCCCCTCCGAGGTCGACGCGCTGATCTCGTGCGCTCTCGACACGACCAATCACAAAAATATCGTAAGCTACCATGGAACGTTCAGGGAAAAGTGCGAGACATGGATCGTTATGGAGTACCTGTCCGGCCCGGAGCTGACCGCATCCATTCGCATGGATGAGGATTCGTGTCGGGAGATCTTTCTGCAGCTGGTCATGGCTGTGCGGCACATACACTCCAAGCACTTTATACACGGTGACCTGAAACCGGAGAACATAATGTTCGAGAACCGAGAGGATAGGACTGTCAAACTGATCGATTTTGGCAGCGCATGTTACAATAATCGCTTTAAGAGCTGGAAGGACAAGCCGCGCTACACGCTGGACTATGCTCCGCCAGAAATGCTCGCGGATGCGAATCTCGTTACTTATTCGCCAGCCGTGGATATATACGGTCTTGGGGCCACGCTGTATACCATGCTGGTGGGTCATCGGCCGTACAGACAGAACGAAGACGATGTGGATCATTCCGCAGCGGCCCATCACGAGCTTCGAAAGCGAATGCGCCGGGGAACGTTTAATCAGCGTTCTATGCGCTGGGAGAGTGCAAGTCCTGCGTTCCGACATTTGGTTAGCTGGTGTCTGCAGCGGGATCCGGCTGATCGGCCCACATTGTCAGATATTCTCGACAGCGAGTGGCTGCAGTACGGCTCAAATGATCCGGACGTGGATATCATTCTGCCACAACAGATGGTTGTGGACCTCAGCGAAGACACTATGGAACAACCGACGGGAGGTATGTTCGACGATCAGCAACAACTGGAATTCATGCACGACAAGTCGGCGGAGGATGAGGGCATAACCCTAGTCAGCGAGCCCATGGATACGACTGTCGCGACTCACGAGTCTAGGAGAAATGCAGCCGCATTTTCGTCGGTAGTTGCTCCAACCACCGACGACGAGATAGTGCACGAACGATTTGACCCGGCATTTGAGGTCCAAGCGGACTTCTACGGTTTCGACGAGAATGCGCCGCCTCTGCCTCTGCCCGAGGAGTACTACTCCGAACTACCTCTGCCAGAGGAGGACCGGCAGTACATACCACCTCCACCAGCACTGATTCCTGTTGAACCAGAAACGACCTTCCGACGGCCAAGAACACGCCAGCAGCGTCGCACTGAAAGCCAGCTAGTACAACCTGTTTCCGTCGCTACGTATGAGGACAGCAAGGCGTCCCTGCGCGTACTAATGCAACAGCTGCCGCCGCCAGGTGACAATGTGGTAGCACGCATTCCGAAGAGAACACATCGAGTCGTACGTACATTGCCTCCGACCTTTGGAACCACCAAGCGAGAAGAGAATTTCTATGGATTTAGTAAGACAGCAATATCGTGGCGAAAGACTCGGGCCAGCTGGCGTCACTTCTGTCTGCTTATCAATGGTGTGCAGCAGGTGCTTAAGGTTCGGTTCAAAAAAGCGCGTCGAGTCTACTGCCTGCCCCATATAAAAGAGGAAAAACTTGATCATGCGTACGAAAAACCGTTGACGTTCCCGCGGCCAAAGGCACAACTGAAGCGCACCAAGCGGGAACCCAAGGTGCCGCGGCCACCGACTCGAGTTCAGCCGGAGAGGGCGCGGGCAATGCGTCAACTTTATCAGTTCCAA

CDS AA Sequence2

MSRLQKQNYEILSGTSTSRLKNHQHPRESESLAYEEPDQMVRNHLNGQLVANGNGKTRKNSNSETMTNGKKSKLNTEGSGSGSGKTLNYNNNNNNNNSISATNGQYTNSSSKTTSASARDYTYRETISPPTPPSPPTTNVADIVCISDAESEDGRDPEREYYDQDMEEDEPNGIEIDESSSSLSKAKSNNAAAAAAAAAAAAAAAASKASSSTTPSYAMPTSNSTPLDLDNEAHQRDLEAVTDLKYYVKLYSDEAVSLNDFKIIRVLGTGAYGRVFLVRKLTRHDAGKLYAMKVLNKITVVQKRKTAEHTKTERVVLEAIQRNPFLVSLHYAFQSSSKLYLVLDFANGGELFTHLYHSENFEESRVRVYIAEVVLALEQLHQLGIIYRDIKLENILLDGEGHIVLSDFGLSKILTAENEYRAHSFCGTLEYMAPEIIRTGPPGHDSAVDWWSVGVLTFELLTGASPFATSDGQVQQSEISRRIQKEQPMIPSSFSANARDFVLKMLEKNPKRRLGGNHRDASEIKEHPFFNGINWQELRTKRRKAPYKPTLTAEDDVQNFSNEFTDQVPEDPECDAPPSRIRLFRGYTYVAPEHLEQMRRDNHCEIQYFNTGLQNIPCRPDDLELGTRTSNGAYGTCHFVVDSSTDLVFLAKIIPLSKFRPSEVDALISCALDTTNHKNIVSYHGTFREKCETWIVMEYLSGPELTASIRMDEDSCREIFLQLVMAVRHIHSKHFIHGDLKPENIMFENREDRTVKLIDFGSACYNNRFKSWKDKPRYTLDYAPPEMLADANLVTYSPAVDIYGLGATLYTMLVGHRPYRQNEDDVDHSAAAHHELRKRMRRGTFNQRSMRWESASPAFRHLVSWCLQRDPADRPTLSDILDSEWLQYGSNDPDVDIILPQQMVVDLSEDTMEQPTGGMFDDQQQLEFMHDKSAEDEGITLVSEPMDTTVATHESRRNAAAFSSVVAPTTDDEIVHERFDPAFEVQADFYGFDENAPPLPLPEEYYSELPLPEEDRQYIPPPPALIPVEPETTFRRPRTRQQRRTESQLVQPVSVATYEDSKASLRVLMQQLPPPGDNVVARIPKRTHRVVRTLPPTFGTTKREENFYGFSKTAISWRKTRASWRHFCLLINGVQQVLKVRFKKARRVYCLPHIKEEKLDHAYEKPLTFPRPKAQLKRTKREPKVPRPPTRVQPERARAMRQLYQFQ

1   H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
2   Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.