Factors @ Stark Lab

Gene Name Type Activity (log2) in S2 cells
(avg/min/max)
Cluster Data available
S2Kc167BG3OSCHeLa
HP1b (FBgn0030082) cofactor
 
(-0.79/-2.68/-0.26)

Factor activity

Additional information

HP1b [FlyBase] | HP1b [FlyMine] | HP1b [BDGP]

H. sapiens orthologues1

CBX1 (HGNC:1551, ENSG00000108468), CBX3 (HGNC:1553, ENSG00000122565), CBX5 (HGNC:1555, ENSG00000094916)

Functionally similar transcription factors and cofactors

CDS DNA Sequence2

ATGGCCGAATTCTCAGTGGAACGCGTCGAGGACAAGCGAACGGTGAACGGACGAACGGAATACTATCTAAAGTGGAAGGGCTATCCGCGCAGCGAAAACACCTGGGAGCCGGTGGAGAATCTCGACTGTCCAGACCTGATAGCCAACTTCGAGGAGTCGCTGAAGAACAACAAGAAGGAGACAAAGAAACGCCTGTCCACCTCCTCCACACCCGAATCCATACGCAGCAAGCGCAAGAGCTTCCTGGAGGACGATACCGAGGAGCAGAAGAAGCTGATCGGCTTTGAGCGCGGTCTGGAGGCATCAAAAATACTGGGCGCCACCGACTCATCCGGGCACCTAATGTTCCTCATGAAGTGGAAGGGCAGCGATCACGCCGACCTTGTGCCCGCCAAGCTGGCCAACACTCGATGCCCCCAGGTGGTCATACAGTTCTATGAGGAGCGCCTCACCTGGCACACGGGCAGCGGCAATGGTAATGGGAATACGAATTCCGTCAATTTGGGATCATCCGGTGGCCTGGGCTCCGTCGGCGGCAGTGGGGCCGGCGATGATACTGCTCCCGGCAGCGTTGGCACCACCGGTGGCGGCAGCAATATAGATGGCGGTGACGAGGAGGATCCCGAACCGGCCAGCCCCATTGGCAGCATCAATCAAGACGAGAATATCAAGCCGGACGAGAGTAGTGAGCTGGACAACGGACAGCCGGATGCGGATGAC

CDS AA Sequence2

MAEFSVERVEDKRTVNGRTEYYLKWKGYPRSENTWEPVENLDCPDLIANFEESLKNNKKETKKRLSTSSTPESIRSKRKSFLEDDTEEQKKLIGFERGLEASKILGATDSSGHLMFLMKWKGSDHADLVPAKLANTRCPQVVIQFYEERLTWHTGSGNGNGNTNSVNLGSSGGLGSVGGSGAGDDTAPGSVGTTGGGSNIDGGDEEDPEPASPIGSINQDENIKPDESSELDNGQPDADD

1   H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
2   Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.