Factors @ Stark Lab

Gene Name Type Activity (log2) in S2 cells
(avg/min/max)
Cluster Data available
S2Kc167BG3OSCHeLa
ph-p (FBgn0004861) TF
 
(-0.91/-3.30/-0.24)

Factor activity

Additional information

ph-p [FlyBase] | ph-p [FlyMine] | ph-p [BDGP]

H. sapiens orthologues1

PHC1 (HGNC:3182, ENSG00000111752), PHC3 (HGNC:15682, ENSG00000173889), PHC2 (HGNC:3183, ENSG00000134686)

Functionally similar transcription factors and cofactors

CDS DNA Sequence2

ATGGATCGTCGTGCATTGAAGTTTATGCAAAAAAGAGCGGACACAGAAAGCGATACGACCACACCCGTGAGCACCACAGCATCCCAGGGGATTTCAGCATCAGCGATTCTAGCAGGAGGCACTCTTCCCTTGAAGGACAACTCGAACATCCGCGAGAAGCCCCTCCACCATAACTACAACCACAATAACAACAACAGCTCCCAGCACTCACACTCGCACCAGCAGCAGCAACAACAGCAGGTGGGTGGCAAGCAGCTCGAGCGGCCACTAAAGTGCCTGGAAACGCTCGCCCAGAAGGCGGGAATCACCTTCGACGAGAAATACGATGTGGCCAGCCCCCCGCATCCCGGCATTGCCCAGCAGCAGGCGACTTCAGGAACAGGCCCAGCAACGGGATCAGGCTCAGTCACCCCCACAAGCCATCGGCACGGAACTCCGCCCACGGGCCGCAGGCAAACCCACACCCCAAGCACTCCGAACAGGCCCAGTGCTCCCAGCACACCCAACACTAACTGCAACTCAATTGCCCGCCACACCAGCCTCACGCTGGAGAAGGCGCAGAATCCCGGCCAGCAGGTGGCCGCCACCACCACGGTGCCACTGCAGATATCCCCTGAGCAGCTGCAGCAGTTCTATGCGAGCAATCCCTACGCCATTCAGGTGAAGCAAGAGTTTCCCACGCACACGACCAGTGGCAGTGGAACTGAACTAAAGCATGCAACCAACATTATGGAAGTTCAGCAGCAGTTGCAGCTGCAGCAGCAGCTGTCGGAAGCCAACGGTGGAGGAGCAGCCTCGGCCGGAGCCGGAGGAGCAGCTAGTCCGGCCAACTCGCAGCAAAGCCAGCAACAGCAGCACTCCACAGCCATCAGCACCATGTCGCCGATGCAATTGGCAGCGGCCACTGGAGGAGTTGGCGGGGATTGGACACAGGGAAGGACGGTGCAGCTAATGCAACCCTCCACCAGTTTCCTGTATCCCCAAATGATTGTGTCGGGAAATCTGTTGCATCCAGGAGGCCTCGGTCAGCAGCCAATCCAGGTGATCACCGCCGGCAAGCCATTCCAAGGCAACGGCCCCCAGATGCTTACCACCACGACTCAAAACGCCAAGCAAATGATCGGTGGCCAAGCGGGATTCGCTGGCGGAAATTACGCGACCTGCATTCCCACAAACCACAATCAATCGCCCCAGACGGTGCTCTTCTCACCGATGAACGTCATTTCGCCACAGCAGCAACAGAACCTGCTGCAATCAATGGCCGCTGCAGCTCAGCAGCAGCAACTCACCCAACAGCAGCAACAGTTTAACCAGCAGCAACAACAGCAGCTTACTCAGCAGCAACAGCAGTTGACAGCTGCTCTGGCCAAGGTGGGAGTGGATGCGCAGGGCAAGCTGGCCCAGAAAGTGGTTCAGAAAGTGACTACCACCAGTAGCGCGGTCCAGGCGGCGACGGGTCCTGGATCTACTGGGTCAACACAGACCCAGCAGGTGCAGCAGGTTCAGCAACAGCAGCAGCAGACCACCCAAACCACTCAGCAGTGCGTGCAGGTTTCACAGTCGACTTTGCCAGTCGGTGTGGGTGGACAGTCTGTTCAGACTGCCCAACTTCTGAACGCTGGCCAAGCGCAACAAATGCAGATTCCCTGGTTCTTACAGAATGCTGCAGGACTGCAGCCGTTTGGGCCAAACCAGATCATCCTGCGAAACCAGCCAGACGGAACCCAAGGCATGTTCATTCAACAGCAACCGGCGACGCAGACTTTGCAGACCCAGCAAAACCAGATTATTCAATGCAACGTGACGCAGACGCCCACTAAGGCACGCACTCAACTGGATGCACTTGCTCCCAAGCAGCAACAGCAGCAGCAGCAGGTTGGCACTACCAACCAGACGCAGCAGCAGCAACTAGCGGTGGCTACTGCCCAGTTGCAGCAACAGCAGCAGCAACTCACTGCAGCAGCTCTGCAGCGACCAGGAGCCCCTGTCATGCCCCACAATGGAACTCAAGTGCGTCCGGCCAGTTCCGTATCCACACAGACTGCCCAGAACCAGAGCCTGCTGAAGGCCAAAATGCGCAACAAGCAGCAGCCGGTGCGCCCCGCTTTAGCCACATTGAAAACCGAAATCGGTCAAGTCGCAGGACAAAATAAGGTAGTAGGCCACCTGACCACCGTGCAGCAGCAGCAACAGGCGACGAATCTCCAGCAGGTGGTTAATGCGGCGGGCAACAAAATGGTTGTGATGAGCACAACGGGCACTCCGATCACCCTGCAGAATGGACAGACCCTTCATGCAGCCACTGCGGCAGGAGTCGACAAGCAGCAACAGCAGCTACAACTGTTTCAGAAACAGCAAATCCTGCAACAACAACAAATGTTGCAACAGCAGATTGCTGCCATTCAAATGCAGCAGCAGCAAGCGGCTGTTCAGGCCCAGCAACAACAGCAGCAACAGGTCTCTCAGCAGCAGCAGGTTAACGCCCAGCAACAGCAAGCGGTGGCGCAACAACAACAGGCAGTCGCGCAGGCTCAGCAACAGCAGAGGGAGCAACAGCAGCAAGTTGCCCAAGCCCAGGCGCAGCATCAACAGGCTCTCGCGAATGCCACTCAGCAAATCCTTCAGGTGGCGCCAAATCAATTCATCACGTCCCACCAGCAACAGCAGCAGCAGCAACTTCACAACCAACTGATACAGCAGCAGCTACAGCAACAGGCGCAGGCACAAGTTCAAGCCCAAGTGCAGGCTCAAGCGCAACAGCAACAACAGCAGCGAGAGCAGCAGCAGAATATTATCCAGCAGATTGTGGTGCAACAGTCTGGAGCGACTTCTCAACAGACTTCCCAGCAGCAACAGCACCACCAATCCGGGCAACTACAGCTAAGTAGCGTGCCCTTCTCAGTTTCTTCGTCAACGACGCCAGCCGGAATAGCTACCTCTAGTGCTCTGCAGGCAGCCCTCTCCGCCTCTGGCGCCATCTTTCAGACAGCTAAGCCGGGTACTTGCAGTTCCTCCTCCCCCACAAGCAGTGTGGTCACAATTACCAACCAGAGCAGCACTCCTTTGGTCACCAGCAGTACGGTGGCCAGTATACAGCAGGCTCAGACGCAATCTGCTCAGGTCCACCAACATCAGCAGCTAATCAGCGCCACAATTGCCGGAGGGACTCAACAACAGCCACAGGGACCGCCATCACTTACACCCACCACAAATCCAATTTTGGCCATGACCTCGATGATGAATGCTACAGTGGGTCACCTTTCCACTGCTCCGCCTGTAACTGTTTCTGTGACAAGCACCGCTGTTACTTCGTCGCCGGGTCAGCTGGTTCTCTTAAGCACGGCTAGTAGCGGTGGAGGAGGTAGCATACCAGCCACGCCCACCAAAGAGACACCTTCGAAAGGGCCCACCGCAACCCTGGTGCCCATTGGTTCGCCCAAGACTCCTGTATCAGGAAAGGACACCTGCACTACCCCCAAATCATCTACTCCTGCCACTGTCAGCGCATCCGTAGAGGCCAGTAGTTCCACAGGCGAAGCCCTGTCCAATGGAGATGCCTCAGATAGGTCTTCCACGCCGTCAAAGGGCGCTACCACTCCCACCAGCAAGCAAAGCAATGCAGCAGTGCAGCCACCGAGTAGCACCACTCCCAACAGTGTCAGTGGGAAAGAAGAGCCGAAGCTGGCAACCTGCGGCAGTTTAACGTCCGCAACATCAACTTCAACCACGACAACGATCACCAATGGGATTGGAGTAGCCAGAACGACAGCCAGCACGGCTGTCTCAACCGCTAGCACAACCACTACCAGTTCTGGCACCTTTATCACAAGTTGCACCAGCACAACCACAACCACCACGTCGAGTATCAGTAATGGATCGAAGGATCTCCCCAAGGCGATGATTAAGCCGAACGTCTTAACTCACGTCATCGATGGCTTCATCATCCAGGAGGCCAACGAGCCATTTCCCGTCACCAGACAGCGATATGCAGACAAAGACGTCAGCGATGAGCCGCCAAAGAAAAAGGCAACCATGCAGGAGGACATCAAGCTAAGTGGAATAGCATCAGCTCCAGGCTCGGATATGGTTGCTTGCGAGCAGTGTGGAAAGATGGAGCACAAAGCAAAGCTGAAACGGAAGCGCTACTGTTCGCCAGGATGCTCGAGGCAGGCAAAGAACGGCATCGGTGGAGTTGGATCAGGAGAGACGAACGGCCTGGGGACAGGTGGTATAGTTGGGGTGGACGCCATGGCATTGGTGGACAGGCTGGATGAAGCCATGGCTGAGGAGAAGATGCAGACAGAGGCCACCCCAAAGCTTTCAGAATCGTTTCCTATTTTGGGAGCCTCAACAGAAGTACCTCCAATGTCACTGCCAGTCCAAGCGGCGATTTCTGCGCCCTCGCCTCTTGCAATGCCTCTAGGATCGCCATTGTCAGTTGCACTTCCAACTCTTGCACCACTGTCTGTAGTCACTTCTGGCGCGGCGCCCAAGTCTTCGGAAGTGAATGGAACAGATCGTCCGCCAATCAGCAGCTGGAGTGTGGACGATGTCAGCAACTTCATTCGAGAACTGCCTGGTTGTCAGGACTACGTGGACGACTTTATACAGCAGGAGATCGACGGCCAAGCGCTTCTGTTGCTCAAGGAGAAGCATTTGGTGAACGCTATGGGCATGAAGCTGGGTCCAGCTCTTAAAATTGTGGCCAAGGTGGAGTCCATTAAGGAGGTCCCGCCACCTGGCGAGGCCAAGGATCCAGGAGCGCAG

CDS AA Sequence2

MDRRALKFMQKRADTESDTTTPVSTTASQGISASAILAGGTLPLKDNSNIREKPLHHNYNHNNNNSSQHSHSHQQQQQQQVGGKQLERPLKCLETLAQKAGITFDEKYDVASPPHPGIAQQQATSGTGPATGSGSVTPTSHRHGTPPTGRRQTHTPSTPNRPSAPSTPNTNCNSIARHTSLTLEKAQNPGQQVAATTTVPLQISPEQLQQFYASNPYAIQVKQEFPTHTTSGSGTELKHATNIMEVQQQLQLQQQLSEANGGGAASAGAGGAASPANSQQSQQQQHSTAISTMSPMQLAAATGGVGGDWTQGRTVQLMQPSTSFLYPQMIVSGNLLHPGGLGQQPIQVITAGKPFQGNGPQMLTTTTQNAKQMIGGQAGFAGGNYATCIPTNHNQSPQTVLFSPMNVISPQQQQNLLQSMAAAAQQQQLTQQQQQFNQQQQQQLTQQQQQLTAALAKVGVDAQGKLAQKVVQKVTTTSSAVQAATGPGSTGSTQTQQVQQVQQQQQQTTQTTQQCVQVSQSTLPVGVGGQSVQTAQLLNAGQAQQMQIPWFLQNAAGLQPFGPNQIILRNQPDGTQGMFIQQQPATQTLQTQQNQIIQCNVTQTPTKARTQLDALAPKQQQQQQQVGTTNQTQQQQLAVATAQLQQQQQQLTAAALQRPGAPVMPHNGTQVRPASSVSTQTAQNQSLLKAKMRNKQQPVRPALATLKTEIGQVAGQNKVVGHLTTVQQQQQATNLQQVVNAAGNKMVVMSTTGTPITLQNGQTLHAATAAGVDKQQQQLQLFQKQQILQQQQMLQQQIAAIQMQQQQAAVQAQQQQQQQVSQQQQVNAQQQQAVAQQQQAVAQAQQQQREQQQQVAQAQAQHQQALANATQQILQVAPNQFITSHQQQQQQQLHNQLIQQQLQQQAQAQVQAQVQAQAQQQQQQREQQQNIIQQIVVQQSGATSQQTSQQQQHHQSGQLQLSSVPFSVSSSTTPAGIATSSALQAALSASGAIFQTAKPGTCSSSSPTSSVVTITNQSSTPLVTSSTVASIQQAQTQSAQVHQHQQLISATIAGGTQQQPQGPPSLTPTTNPILAMTSMMNATVGHLSTAPPVTVSVTSTAVTSSPGQLVLLSTASSGGGGSIPATPTKETPSKGPTATLVPIGSPKTPVSGKDTCTTPKSSTPATVSASVEASSSTGEALSNGDASDRSSTPSKGATTPTSKQSNAAVQPPSSTTPNSVSGKEEPKLATCGSLTSATSTSTTTTITNGIGVARTTASTAVSTASTTTTSSGTFITSCTSTTTTTTSSISNGSKDLPKAMIKPNVLTHVIDGFIIQEANEPFPVTRQRYADKDVSDEPPKKKATMQEDIKLSGIASAPGSDMVACEQCGKMEHKAKLKRKRYCSPGCSRQAKNGIGGVGSGETNGLGTGGIVGVDAMALVDRLDEAMAEEKMQTEATPKLSESFPILGASTEVPPMSLPVQAAISAPSPLAMPLGSPLSVALPTLAPLSVVTSGAAPKSSEVNGTDRPPISSWSVDDVSNFIRELPGCQDYVDDFIQQEIDGQALLLLKEKHLVNAMGMKLGPALKIVAKVESIKEVPPPGEAKDPGAQ

1   H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
2   Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.