Factors @ Stark Lab

Gene Name Type Activity (log2) in S2 cells
(avg/min/max)
Cluster Data available
S2Kc167BG3OSCHeLa
org-1 (FBgn0021767) TF
 
(0.66/-1.05/2.90)

Factor activity

Additional information

org-1 [FlyBase] | org-1 [FlyMine] | org-1 [BDGP]

H. sapiens orthologues1

TBX5 (HGNC:11604, ENSG00000089225), TBX4 (HGNC:11603, ENSG00000121075)

Functionally similar transcription factors and cofactors

CDS DNA Sequence2

ATGACGCACCTGATGGGCCCCACTGAGTGCGCCGGCGCCATGATGACCACCACATCCATGCAGTTCCTGGACACCAGCCTAACGGACTACAACTGCTATGGCAACGACTACTGGACATCGCCGTACATGACCGGCGGACTCAGTCCCATGAAGCAGATCGAAGCCTGCATCCAAACGGCTGGCAAGGATCGCAGCTCGTACAAGCCGCTGGAGCAGATCGATGCCAAATTGGCGGACATCGAGACGCACAGTACAGGCAGCACTGGCACCGCGAACAGCAACAGCAGCACCAGCAGCATCTCGAATCCCAGTTGCCCGGATCAGTCGTCGTCGTCGTCATCGTCGTCCGTATCGCTGCCAACCGATTATGCCGGCGTACACAGTGAAGCCTCGATGGCACCAACAGCCGGCGGCACGGCAGTCACAACGACATCAGCTGGCGGAGTCAGTGCATCCACCGCGTCCAAAAAGTTCAAGGGACAGCACAAAAAAGACAACAACAGTGCGGAGAACGGTACAGTGAAGCCCAATAGCCATAATATCAGCAAAGGTGAATCGGAGCCAGTGCATCCATCGCTGGCCCAGGCCATTGTGGTGCTGGAGACGAAGGCGCTGTGGGATCAGTTCCATGCCCAGGGCACCGAAATGATCATCACCAAGACGGGCCGACGCATGTTTCCCACGTTTCAGGTGAGGATCGGTGGTTTGGATCCACATGCCACCTACATTTGCATGATGGACTTTGTGCCCATGGATGACAAACGCTATCGCTACGCCTTTCACAACTCCTGCTGGGTGGTGGCTGGCAAGGCGGATCCCATTTCCCCGCCCAGGATTCATGTGCATCCCGACTCGCCAGCCGTCGGCTCCAATTGGATGAAGCAGATCGTGTCCTTTGACAAATTGAAGCTCACCAATAACCAGCTGGACGAAAATGGACATATCATTCTGAACTCCATGCATCGCTACCAGCCGCGTTTCCATCTGGTTTATCTGCCACCGAAGAACGCCTCCTTGGATGAGAACGAGCACTCCAGCCACTTTCGCACTTTCATCTTTCCGGAAACGAGCTTTACGGCCGTAACTGCCTACCAGAATCAGCGGGTGACACAGCTGAAGATCTCCAGCAATCCATTCGCCAAAGGCTTTCGGGATGATGGCACCAACGATGTAACCACTGGCGGTGGCAGCAGCATGTCCTCCATGAGTCACGAAAGTCAGGCGCGCATGAAGCAGCAACAGCAGCAGCAGCAGCAGCAGCAGCAGCAACTGCAGCAGCAACAGCAACAGCAGCAGCAACTCAAGGAGCGAACGGCAGCAACCAGCAACTTTGGCCTGAGTTGCAGCGAACTGGCCATTGAGCAACAGCAGCAGCAGCAACAGCAACAGGGAGTTCTGCAGCTACCGGCCACGCCCTCCAGCAGCTCCACCTCCGGCAATTCACCCGACTTGCTGGGCTACCAGATGGAGCAGCAACTGCAACAGCAACACCAACAGCAGCAGCAACAGCAACACCAGTCCCAGCAGCAACATCTCCACCAGCAACACCAGGCTAACCAGCAACAATCGCTGCTCCAACAGAGCCAGAATCACACGCAATATGGCAGCTATCATCATGCGTACCAGGCACAGGTGCAGTCGCATCCCCTAACGCCGCACTCCAGCAGCTCCGCATCCCCGCCAGCAACTGCTGCGCCGGGCGCAAGTGCAGCAACAGCAGCAGTAGCGGGAGGAGCAGGAGCAGCAGGAGCAGGCGGAGCAACGTCAGCCACACAAGTGATGAGTGCGGCCAATATCTATTCGAGCATTGGACAACCCTATGCCCAGGAGCAGAGCAACTTTGGTGCGATCTACCATCATAATGCTGCTGCCGCAGCGGCCGCTCACTATCATCATGGTCATGCCCACGGCCACGCCCATAGCCATGCGCACGCCCACGCCCACGGACCATATGCCAGCGCCTACGACAAGCTGAAGGTGTCGCGTCATGCGGCAGCTGCCGCCTATGGCATGGGCGCCACCTATCCAAGTTTTTACGGTTCGGCTGCACATCACCAGATGATGCGACCGAATAGCTACATAGATCTGGTGCCGCGC

CDS AA Sequence2

MTHLMGPTECAGAMMTTTSMQFLDTSLTDYNCYGNDYWTSPYMTGGLSPMKQIEACIQTAGKDRSSYKPLEQIDAKLADIETHSTGSTGTANSNSSTSSISNPSCPDQSSSSSSSSVSLPTDYAGVHSEASMAPTAGGTAVTTTSAGGVSASTASKKFKGQHKKDNNSAENGTVKPNSHNISKGESEPVHPSLAQAIVVLETKALWDQFHAQGTEMIITKTGRRMFPTFQVRIGGLDPHATYICMMDFVPMDDKRYRYAFHNSCWVVAGKADPISPPRIHVHPDSPAVGSNWMKQIVSFDKLKLTNNQLDENGHIILNSMHRYQPRFHLVYLPPKNASLDENEHSSHFRTFIFPETSFTAVTAYQNQRVTQLKISSNPFAKGFRDDGTNDVTTGGGSSMSSMSHESQARMKQQQQQQQQQQQQLQQQQQQQQQLKERTAATSNFGLSCSELAIEQQQQQQQQQGVLQLPATPSSSSTSGNSPDLLGYQMEQQLQQQHQQQQQQQHQSQQQHLHQQHQANQQQSLLQQSQNHTQYGSYHHAYQAQVQSHPLTPHSSSSASPPATAAPGASAATAAVAGGAGAAGAGGATSATQVMSAANIYSSIGQPYAQEQSNFGAIYHHNAAAAAAAHYHHGHAHGHAHSHAHAHAHGPYASAYDKLKVSRHAAAAAYGMGATYPSFYGSAAHHQMMRPNSYIDLVPR

1   H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
2   Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.