Factors @ Stark Lab

Gene Name Type Activity (log2) in S2 cells
(avg/min/max)
Cluster Data available
S2Kc167BG3OSCHeLa
alpha-Adaptin (FBgn0263350) cofactor
 
(-0.25/-2.49/0.41)

Factor activity

H. sapiens orthologues1

AP2A2 (HGNC:562, ENSG00000183020), AP2A1 (HGNC:561, ENSG00000196961)

Functionally similar transcription factors and cofactors

CDS DNA Sequence2

ATGGAGAGAGCTGAAGGGTGTGAAGTCGTCTCTCCGATCGATCAATCGCGGGGTGGAAAGGAAAGCGAAGCTTCCGCAGACGAATCACTGTTGTTTTACTGCAAAAGCAAAGAGGCCGAAGTCAAACGCATAAACAAGGAGTTGGCCAATATACGAAGCAAATTTAAAGGAGACAAAACCCTCGACGGCTATCAGAAAAAGAAATATGTCTGTAAGCTATTATTCATATTTCTCCTCGGCCATGACATCGACTTCGGGCACATGGAGGCGGTCAATTTGCTGTCCTCCAACAAATACTCAGAAAAGCAGATTGGTTACCTTTTCATCTCAGTGTTGGTGAACACCAACAGCGACCTTATTCGGCTGATCATCCAATCTATAAAGAATGATTTGCAGTCGCGTAATCCTGTGCACGTTAATCTGGCACTACAATGCATTGCCAACATTGGAAGTCGGGATATGGCCGAGTCCTTTTCCAACGAAATACCCAAGCTACTCGTCTCGGGCGACACCATGGACGTGGTGAAGCAGTCGGCGGCGCTATGCCTGCTCCGCCTGTTCCGCTCCTCGCCGGACATCATTCCCGGTGGTGAGTGGACTTCGCGCATTATCCATTTGCTCAATGATCAGCACATGGGAGTGGTCACAGCGGCCACCTCGCTGATCGACGCCTTGGTGAAGCGCAATCCGGACGAGTACAAGGGTTGTGTTAATTTGGCTGTTTCACGCTTATCCCGGATCGTAACAGCCAGCTACACGGATCTTCAGGATTACACATATTACTTTGTGCCGGCTCCATGGCTATCGGTGAAACTTCTGCGATTGCTGCAAAACTACAATCCAGTGACCGAAGAGGCCGGTGTGCGGGCCCGCTTGAATGAAACTTTGGAGACGATTTTGAACAAGGCGCAAGAGCCGCCAAAGAGTAAGAAGGTGCAGCACTCTAACGCAAAGAACGCCGTGCTCTTCGAGGCCATCAACCTGATCATTCACAGCGACAGCGAGCCGAACCTTCTTGTCCGCGCTTGCAACCAGTTGGGACAGTTCCTTAGCAATCGGGAGACCAACTTGCGCTATCTGGCTCTGGAGTCCATGTGCCACCTGGCCACATCGGAGTTCTCGCACGAGGAGGTGAAGAAGCACCAGGAGGTGGTCATTTTGTCAATGAAAATGGAGAAGGACGTGTCCGTGCGCCAAATGGCGGTGGATCTTTTGTATGCCATGTGTGATCGTGGTAATGCCGAGGAAATTGTTCAGGAGATGCTCAACTATCTGGAGACGGCCGACTACTCTATTCGTGAGGAAATGGTGCTCAAGGTGGCCATTCTTGCCGAGAAGTACGCCACGGATTATACCTGGTATGTGGACGTTATCCTCAATCTAATTCGCATTGCTGGCGACTACGTGTCTGAGGAAGTATGGTACCGCGTCATTCAGATCGTGATCAATCGCGAGGAGGTTCAAGGCTATGCCGCAAAGACTGTTTTTGAGGCGCTACAGGCCCCTGCCTGCCACGAAAACATGGTTAAAGTGGGCGGCTACATCTTGGGCGAGTTTGGCAACTTAATCGCCGGAGATTCCCGCTCAGCACCACTGGTACAATTCAAGCTACTGCACTCCAAGTACCACTTGTGCTCGCCGATGACCCGGGCCCTTCTTCTGTCCACGTACATTAAATTTATCAACCTCTTTCCGGAAATTCGTACCAATATCCAGGATGTGTTCCGCCAGCACAGCAATCTTCGATCCGCAGATGCGGAACTGCAGCAGCGAGCTAGCGAATATCTCCAGCTTAGCATAGTGGCATCGACAGACGTTTTGGCCACCGTCCTGGAGGAGATGCCATCGTTCCCGGAACGCGAGAGCTCAATTTTAGCAGTGCTAAAGAAGAAGAAGCCCGGCAGGGTGCCGGAGAACGAAATTCGCGAGTCGAAGAGCCCGGCACCCCTGACTTCTGCAGCGCAGAACAACGCCCTTGTGAACAATTCACATAGCAAGCTGAATAACAGCAACGCAAATACGGATCTGCTTGGATTAAGCACTCCGCCATCAAATAATATTGGCAGTGGTAGCAATAGCAACAGTACGCTCATTGATGTTTTGGGCGACATGTACGGCAGCAATAGTAACAACAACTCAAGTGCCGTGTACAACACGAAGAAGTTTTTGTTCAAGAACAATGGTGTTTTGTTTGAGAACGAAATGCTGCAGATCGGTGTGAAGAGCGAGTTTCGCCAGAATTTAGGACGATTAGGCCTTTTCTACGGCAACAAGACACAGGTTCCCCTGACAAACTTCAATCCTGTGCTGCAATGGTCTGCCGAGGATGCGCTTAAGCTGAACGTGCAGATGAAGGTGGTGGAGCCAACCCTGGAGGCCGGCGCCCAGATCCAACAACTGTTAACCGCGGAATGCATCGAGGACTACGCCGATGCGCCAACAATCGAGATCAGTTTCCGCTACAACGGCACCCAGCAGAAGTTCAGCATTAAACTGCCATTGAGCGTTAACAAATTCTTTGAGCCTACCGAAATGAATGCGGAATCATTCTTTGCACGATGGAAGAACCTTAGCGGTGAACAACAACGGTCACAGAAAGTGTTCAAGGCTGCACAGCCACTGGATTTGCCCGGAGCCCGCAACAAGCTTATGGGCTTTGGAATGCAACTGCTGGACCAAGTGGATCCCAATCCAGACAACATGGTCTGCGCGGGCATCATTCATACGCAATCGCAACAGGTGGGCTGCCTTATGCGATTGGAGCCGAACAAGCAGGCTCAGATGTTCCGACTGACAGTTCGGGCAAGCAAGGAGACCGTAACTCGGGAAATCTGCGATCTGTTGACGGATCAATTC

CDS AA Sequence2

MERAEGCEVVSPIDQSRGGKESEASADESLLFYCKSKEAEVKRINKELANIRSKFKGDKTLDGYQKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNKYSEKQIGYLFISVLVNTNSDLIRLIIQSIKNDLQSRNPVHVNLALQCIANIGSRDMAESFSNEIPKLLVSGDTMDVVKQSAALCLLRLFRSSPDIIPGGEWTSRIIHLLNDQHMGVVTAATSLIDALVKRNPDEYKGCVNLAVSRLSRIVTASYTDLQDYTYYFVPAPWLSVKLLRLLQNYNPVTEEAGVRARLNETLETILNKAQEPPKSKKVQHSNAKNAVLFEAINLIIHSDSEPNLLVRACNQLGQFLSNRETNLRYLALESMCHLATSEFSHEEVKKHQEVVILSMKMEKDVSVRQMAVDLLYAMCDRGNAEEIVQEMLNYLETADYSIREEMVLKVAILAEKYATDYTWYVDVILNLIRIAGDYVSEEVWYRVIQIVINREEVQGYAAKTVFEALQAPACHENMVKVGGYILGEFGNLIAGDSRSAPLVQFKLLHSKYHLCSPMTRALLLSTYIKFINLFPEIRTNIQDVFRQHSNLRSADAELQQRASEYLQLSIVASTDVLATVLEEMPSFPERESSILAVLKKKKPGRVPENEIRESKSPAPLTSAAQNNALVNNSHSKLNNSNANTDLLGLSTPPSNNIGSGSNSNSTLIDVLGDMYGSNSNNNSSAVYNTKKFLFKNNGVLFENEMLQIGVKSEFRQNLGRLGLFYGNKTQVPLTNFNPVLQWSAEDALKLNVQMKVVEPTLEAGAQIQQLLTAECIEDYADAPTIEISFRYNGTQQKFSIKLPLSVNKFFEPTEMNAESFFARWKNLSGEQQRSQKVFKAAQPLDLPGARNKLMGFGMQLLDQVDPNPDNMVCAGIIHTQSQQVGCLMRLEPNKQAQMFRLTVRASKETVTREICDLLTDQF

1   H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
2   Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.