Factors @ Stark Lab

Gene Name Type Activity (log2) in S2 cells
(avg/min/max)
Cluster Data available
S2Kc167BG3OSCHeLa
egg (FBgn0086908) cofactor
 
(-0.19/-2.41/0.60)

Factor activity

Additional information

egg [FlyBase] | egg [FlyMine] | egg [BDGP]

H. sapiens orthologues1

SETDB1 (HGNC:10761, ENSG00000143379)

Functionally similar transcription factors and cofactors

CDS DNA Sequence2

ATGTCTGGGCAGCCAACAGCCGTGGACTGCTTAGAGAGCAGTGGAAGCACAGTGGAGGATGTCCAAGAAACACCGGCGTCGAGGGAAAAAAGTTACGGGTTGCCGGTGCGCAAAGGAGAAAATAGCTTGGAGTCTCCTGCAGAACAAGCCGCAAAGGATGTGGAAATTGAGGAACTGACACACAGTGAAGCAATCGCCGCCACCGGTTCAACCAGGAAGCAGTGCCCATATGGAGGTAAGGCCCCTGATGAACCTGGAAAGTTGGCCGACGAATCGGAGGACCGCAAGGGAGAGAACACGAAAGCCATTGCAAGCAGCCCGGTTTTGGTAGCTGTGGATTCGGACAGCAGTGTTGAGCTAATAGAGAGTCCTGTCAAATTCTCCTCCGCCAACGAAAGTGAGAAAGATCCGCCAAAACCAGATGCTGTCAATGAAGCTGCGGCTAAAGAGGCCGAGGAAATGACTGATAGCAGCATCAGCAGTCCCACATCCGAAAGTTTTCCTGAAAAAGATGAAAAGACCAATAAGGAAAATGAGCAAGAACCTCCTGGCATGGAGGTAGATCAGGACGTCGAGGAGTCAATAAGTCGACCAGCAGAAGAATACAAAATTGAGAATACATTAAAAGGTCACAAGCGTATTAGCTTAACGGAAATCGAAGAACACAAAATTGTTGATAAAAAAGACGATGTCCTAGAGGTGGAGCTTGAAAAGGGCACTGCTCCGAAAGCTGCAGAAGACGAGAAGCTGAACGCTTTGTTATCAGATGGAGATGTCTTCTACGACAAGGAATGTGTCAACTGCAATTGCACAAAGCTTCATAAACAGTACGTGTTGGCTAACATGGCCACTTTAAACTTTTACCAGGTGCTCCGAAAGTCTTCCAAGCAGCAGTTCCTCTGCATGGGATGCCATGACACAGCAATGGACTTGTATGAGGAGTATGCTGGACAACTAATGGCCAAGCAGCCGCTGCTGCTAAAGGATTTCCATCAGGATCACGCCGACTTTGTGGCTCTGGACAGCAGCGATGAGGAGGAAGAGGAGAAGCAGCCAGAAAAATCGGACTTTTCGAAAAACAAGCTGCAGCTCATCGAAGATGAACTCGATGATGCCATCAAAAATGTACTTAACAAGGTGGATTTTACGGCTCAGCTGTCCTGGTCAAAAACTATTCTCCAGGCGAAAGCAGACCACTTGGAGCGACAATTCGCACTGGCAGATGTGGAACTCGAAAAAGTTCAGACCACCGCTGACAAAATGCACTGCGCTTTGTATAACTCGTGTCCGGTGGCACACAAACATCTGCCCACCCTGGACATTGAACCCAGTGACTATGTGCATGAAGTTCCACCTCCTGGCGAAATCGTGCGTCCTCCAATACAGTTGGGAGAGACATACTACGCTGTTAAGAACAAGGCTATTGCCAGCTGGGTGTCCATAAAGGTAATCGAGTTTACAGAGAGCACCGCCATCAACGGAAACACGATGAAGAGCTACAAGATTAGGTACCTCAACACTCCGTACCAGATGATCAAGACAGTGACGGCCAAGCACATTGCCTACTTCGAACCACCGCCAGTGCGACTGACCATTGGTACCCGCGTGATTGCGTACTTCGATGGCACCACTTTGTCGCGGGGCAAGGATAAGGGCGTGGTGCAGAGCGCCTTTTATCCAGGCATCATCGCTGAGCCGTTGAAGCAGGCCAATCGCTACCGCTACCTAATATTCTACGACGATGGGTACACTCAGTACGTTCCGCACCGCGATGTCCGTCTAGTTTGCCAGGCTTCCGAGAAAGTGTGGGAGGACGTACACGCCGCATCGCGCGATTTCATACAGAAGTACGTGGAGAAGTACTCCGTGGATCGTCCAATGGTGCAATGCACCCGGGGACAAAGTATGACCACTGAATCGAACGGGACCTGGCTGTACGCGCGCGTCATTGACATCGACTGCAGCTTGGTGTTGATGCAGTTTGAGGGCGACAAAAACCATACGGAGTGGATATACAGGGGTTCATTGCGCTTGGGTCCTGTCTTCAGGGAAACCCAGAACAATATGAACAGTTCAAGCGCACAGCAGCTGCGTGTCCCAAGACGCACGGAGCCCTTTATTCGGTACACCAAGGAGATGGAGTCCAGCAGCAAGGTGAACCAGCAGATGCGTGCCTTTGCCCGCAAGAGCAGCGCCTCCGCCCAAAATAACGCATTAGCGGCTGCATCTTCGGCAGCAACCCCAGCCGGAGGACGCACCAATGCAGGAGGTGTCAGCACCAGTAATAGCGCAAGTGCTGTGCGACACCTAAACAACTCGACAATCTACGTGGACGACGAGAACAGGCCCAAGGGCCATGTAGTCTACTTTACAGCCAAGCGGAATCTGCCTCCCAAAATGTACAAGTGCCACGAGTGCAGCCCGAACTGCCTCTTTAAGATCGTTCACCGTCTGGACAGCTACAGTCCGTTAGCGAAGCCTCTGCTTTCTGGCTGGGAACGTCTTGTCATGCGGCAGAAGACCAAGAAGTCTGTGGTATACAAGGGACCTTGTGGCAAAAGCTTGCGCAGCCTGGCCGAAGTTCACAGGTACCTTCGAGCTACTGAAAATGTGTTGAACGTAGACAATTTTGACTTTACGCCCGACCTCAAGTGTCTGGCCGAGTACTCCATTGATCCCTCGATCGTGAAGGACACGGACATTTCAAAGGGGCAGGAGAAGATGGCGATTCCGCTGGTAAACTACTACGACAACACCCTGCCGCCCCCATGCACCTACGCGAAGCAGCGCATCCCTACCGAGGGTGTTCATCTGAATCTGGACGAGGAGTTCCTCTTGTGCTGCGACTGCGAGGACGACTGCTCGGACAAGTCAAAGTGCGCCTGTTGGCAGCTAACGGTGGCGGGCGTGCGGTACTGTAACCCGAAGAAACCCATCGAGGAGATAGGCTACCAGTACAAGCGGCTCCACGAGCACGTGCCCACCGGCATCTACGAGTGCAACTCGCGCTGCAAGTGCAAGAAGAATTGCCTGAACCGGGTGGTGCAGTTCTCCCTAGAGATGAAACTGCAGGTGTTCAAGACCTCAAATCGTGGATGGGGCTTGCGCTGCGTTAACGACATCCCCAAGGGTGCTTTCATCTGTATTTACGCCGGCCATCTGCTCACGGAGACGATGGCCAACGAAGGCGGACAGGACGCCGGCGACGAGTATTTCGCGGACTTAGATTACATAGAGGTCGCTGAACAGTTAAAAGAGGGATACGAGTCGGAGGTGGACCACTCGGACCCGGACGCCGAGGAGGACAACGGGGGACCCGATGCCGAGGACGATGACGACTTCCGGCCAAACTATCACTACCAGCGCAAAATCAAGCGCTCTTCCAGAAGCGGCTCCACGCAGAACAGCTCCACTCAGAGCAGCGAGTTGGACTCGCAGGAGCGTGCGGTGATCAACTTTAACCCAAATGCTGATCTGGACGAGACGGTGCGGGAGAACTCGGTGCGGAGGCTTTTCGGCAAGGACGAGGCGCCCTACATCATGGACGCCAAGACAACGGGCAACCTTGGACGCTATTTCAACCACTCGTGCAGCCCCAATCTCTTCGTGCAGAACGTGTTCGTGGATACTCACGACCTGCGTTTCCCCTGGGTTGCCTTCTTCTCGGCCGCGCACATCCGCTCCGGCACCGAGCTGACTTGGAACTACAATTACGAGGTGGGCGTGGTGCCCGGCAAGGTGTTGTACTGCCAGTGCGGGGCCCCCAATTGCCGCCTTCGTCTGCTC

CDS AA Sequence2

MSGQPTAVDCLESSGSTVEDVQETPASREKSYGLPVRKGENSLESPAEQAAKDVEIEELTHSEAIAATGSTRKQCPYGGKAPDEPGKLADESEDRKGENTKAIASSPVLVAVDSDSSVELIESPVKFSSANESEKDPPKPDAVNEAAAKEAEEMTDSSISSPTSESFPEKDEKTNKENEQEPPGMEVDQDVEESISRPAEEYKIENTLKGHKRISLTEIEEHKIVDKKDDVLEVELEKGTAPKAAEDEKLNALLSDGDVFYDKECVNCNCTKLHKQYVLANMATLNFYQVLRKSSKQQFLCMGCHDTAMDLYEEYAGQLMAKQPLLLKDFHQDHADFVALDSSDEEEEEKQPEKSDFSKNKLQLIEDELDDAIKNVLNKVDFTAQLSWSKTILQAKADHLERQFALADVELEKVQTTADKMHCALYNSCPVAHKHLPTLDIEPSDYVHEVPPPGEIVRPPIQLGETYYAVKNKAIASWVSIKVIEFTESTAINGNTMKSYKIRYLNTPYQMIKTVTAKHIAYFEPPPVRLTIGTRVIAYFDGTTLSRGKDKGVVQSAFYPGIIAEPLKQANRYRYLIFYDDGYTQYVPHRDVRLVCQASEKVWEDVHAASRDFIQKYVEKYSVDRPMVQCTRGQSMTTESNGTWLYARVIDIDCSLVLMQFEGDKNHTEWIYRGSLRLGPVFRETQNNMNSSSAQQLRVPRRTEPFIRYTKEMESSSKVNQQMRAFARKSSASAQNNALAAASSAATPAGGRTNAGGVSTSNSASAVRHLNNSTIYVDDENRPKGHVVYFTAKRNLPPKMYKCHECSPNCLFKIVHRLDSYSPLAKPLLSGWERLVMRQKTKKSVVYKGPCGKSLRSLAEVHRYLRATENVLNVDNFDFTPDLKCLAEYSIDPSIVKDTDISKGQEKMAIPLVNYYDNTLPPPCTYAKQRIPTEGVHLNLDEEFLLCCDCEDDCSDKSKCACWQLTVAGVRYCNPKKPIEEIGYQYKRLHEHVPTGIYECNSRCKCKKNCLNRVVQFSLEMKLQVFKTSNRGWGLRCVNDIPKGAFICIYAGHLLTETMANEGGQDAGDEYFADLDYIEVAEQLKEGYESEVDHSDPDAEEDNGGPDAEDDDDFRPNYHYQRKIKRSSRSGSTQNSSTQSSELDSQERAVINFNPNADLDETVRENSVRRLFGKDEAPYIMDAKTTGNLGRYFNHSCSPNLFVQNVFVDTHDLRFPWVAFFSAAHIRSGTELTWNYNYEVGVVPGKVLYCQCGAPNCRLRLL

1   H. sapiens orthologs were obtained from InParanoid8, in particular D.melanogaster-H.sapiens.orthoXML.
2   Genomic sequences of the transcription factors were obtained from the dm3/BDGP Release 5 genome assembly. In the case of cofactors, the genomic sequences stand for our results obtained by deep sequencing.